Results 91 to 100 of about 6,001 (279)

Decoding IGLL5 Mutation‐Mediated BCR Signaling: A Novel Mechanism of CD8+ T Cell Exhaustion and Ocular MALT Lymphoma Progression

Advanced Science, EarlyView.
OAML harbors recurrent IGLL5 mutations that reinforce CD79A/CD79B‐associated BCR signaling. Mechanistic analysis of the S47G and A54G variants reveals induction of CXCL10/CXCL11, enhanced CD8+ T‐cell recruitment, and exhaustion‐associated dysfunction, supporting an immune‐tolerant niche.
Andi Zhao, Haoyu Wei, Chenyu Zhou, Xinping Sun, Shuyan Da, Haiyu Liu, Zijin Wang, Hui Zhu, Shiya Shen, Qing Shao, Qi Gong, Hu Liu, Xuejuan Chen   +12 more
wiley   +1 more source

Time-Series Monitoring and Mechanism Analysis of Surface Subsidence in Changchun City Using E-PS-InSAR

Remote Sensing
Surface subsidence has grown to be a major geological problem for big and medium-sized cities in the context of urbanization and climate change. Changchun, a city of moderate size and rapid development, was chosen as the study region for this project ...
Yunqi Liu, Ying Yang, Kaining Li, Di Liang, Chuanzeng Shu, Zhiguo Meng, Qing Ding   +6 more
doaj   +1 more source

Application of GPS technology in surface subsidence monitoring of water extraction

Desalination and Water Treatment, 2021
Aigong Xu, Qiushi Yang, Huizhong Zhu, Meng Gao   +3 more
openaire   +1 more source

Analysis of Excavation with Numerical Simulation and Monitoring Data Has Effect on Surface Subsidence

DEStech Transactions on Materials Science and Engineering, 2017
Excavations cause the settlement of surrounding soil and have other adverse effects on surrounding buildings, traffic, underground facilities and so on. In this paper, a three-dimensional model is established by finite element software Midas/GTS based on the top-down excavation of underground works in Hefei New Traffic Building.
Ke-wei DING, Xiao WANG
openaire   +2 more sources

A new monitoring strategy to control land movements. The Veneto Region test area

, 2005
Anthropogenic land subsidence has widely been affecting the Veneto Region, northern Italy, since the past century. Groundwater withdrawals for industriai, domestic, and agri cultura!
Tosi, Luigi, Rizzetto, Federica, Strozzi, Tazio, Carbognin, Laura, Teatini, Pietro, Vitturi, Andrea   +5 more
core  

Corals and Reef‐Dwelling Fish Regulate Carbon Storage and Cycling Processes in Coral Reef Ecosystems

Advanced Science, EarlyView.
Coral reefs are biodiversity hotspots, yet their role in carbon storage and cycling remains poorly understood. Using field surveys and modeling in the South China Sea, we reveal the overlooked potential of carbon storage in reef ecosystems and how reef fish, corals, and surface sediment jointly shape reef carbon reservoirs.
Yiting Chen, Wenliang Zhou, Lan Qiu, Han Lai, Mingpan Huang, Qian Li, Wen Yu, Pei‐Yuan Qian, Fuwen Wei   +8 more
wiley   +1 more source

Near Real-Time Monitoring of Large Gradient Nonlinear Subsidence in Mining Areas: A Hybrid SBAS-InSAR Method Integrating Robust Sequential Adjustment and Deep Learning

Remote Sensing
With the increasing availability of satellite monitoring data, the demand for storage and computational resources for updating the results of monitoring the surface subsidence in a mining area continues to rise.
Yuanjian Wang, Ximin Cui, Yuhang Che, Yuling Zhao, Peixian Li, Xinliang Kang, Yue Jiang   +6 more
doaj   +1 more source

Integrating field and numerical modeling methods for applied urban karst hydrogeology [PDF]

, 2009
Infrastructures constructed on unstable geologic formations are prone to subsidence. Data have been collected in the context of an upgrading project for a highway located beside a river dam constructed on gypsum-bearing formations.
J. Epting, D. Romanov, Epting, J., Kaufmann, G., Romanov, D., Huggenberger, P., P. Huggenberger, G. Kaufmann   +7 more
core  

HNRNPD Induces Radioresistance in Nasopharyngeal Carcinoma by Sequestering GRAMD4 mRNA in Stress Granules

Advanced Science, EarlyView.
HNRNPD promotes radioresistance in nasopharyngeal carcinoma by enhancing stress granule assembly and sequestering GRAMD4 mRNA. This suppresses GRAMD4 translation and inhibits mitochondrial apoptosis. Targeting the integrated stress response with ISRIB restores GRAMD4 expression and sensitizes tumors to radiotherapy, revealing a translational control ...
Yingzi Li, Tong Xiang, Yuanyuan Liu, Desheng Weng, Jingjing Zhao, Hao Chen, Yan Tang, Songzuo Xie, Hao Zhang, Jun Luo, Xinyi Yang, Qiuzhong Pan, Muping Di, Jianchuan Xia   +13 more
wiley   +1 more source

Lilrb4a Suppression Reprograms Microglia to Mitigate APOE4‐Associated Amyloid Plaques and Cerebral Amyloid Angiopathy in Association With a PPAR‐Linked Pro‐Clearance State

Advanced Science, EarlyView.
Targeting Lilrb4a in Apolipoprotein E4 (APOE4)‐associated Alzheimer's disease (AD) reprograms microglia toward a beneficial, phagocytic state. Genetic deletion or antisense inhibition of Lilrb4a suppresses p‐SHP2/NF‐κB/STAT1 signaling, restores PPAR‐linked lipid and energy metabolism, and reduces amyloid plaque burden and cerebral amyloid angiopathy ...
Changxu Nie, Ruixi Yang, Xiaotong Wang, Ping Jia, Xueqi Zhang, Yaqi Dai, Xue Bai, Sijia Duan, Yufeng Li, Peng Zheng, Xin Tian, Li Jiang, Chao Wang   +12 more
wiley   +1 more source