Results 111 to 120 of about 6,001 (279)

Engineering Neuronal Network Connectivity Through Precise and Scalable Electrical Modulation

Advanced Science, EarlyView.
This study presents a scalable all‐electrical method for precise neuronal‐circuit reconfiguration based on high‐density microelectrode arrays. By employing biologically inspired plasticity rules, targeted connectivity changes were successfully induced and quantified across diverse neuronal preparations.
Sreedhar S. Kumar, Yannaël Bossard, Rachel Sava, Tobias Gänswein, Lorenca Sadiraj, Jean‐Samuel Dupré, Manuel Schröter, J. Gray Camp, Fernando Cardes, Julian Bartram, Andreas Hierlemann   +10 more
wiley   +1 more source

Construction of High-Precision and Complete Images of a Subsidence Basin in Sand Dune Mining Areas by InSAR-UAV-LiDAR Heterogeneous Data Integration

Remote Sensing
Affected by geological factors, the scale of surface deformation in a hilly semi-desertification mining area varies. Meanwhile, there is certain dense vegetation on the ground, so it is difficult to construct a high-precision and complete image of a ...
Rui Wang, Shiqiao Huang, Yibo He, Kan Wu, Yuanyuan Gu, Qimin He, Huineng Yan, Jing Yang   +7 more
doaj   +1 more source

Dynamic Surface Subsidence Characteristics due to Super-Large Working Face in Fragile-Ecological Mining Areas: A Case Study in Shendong Coalfield, China

Advances in Civil Engineering, 2019
The dynamic subsidence characteristics due to super-large working face (SLWF) are the basis for further understanding of land ecology damage in fragile-ecological mining areas.
Chao Chen, Zhenqi Hu, Jin Wang, Jitang Jia   +3 more
doaj   +1 more source

A New Customizable Surfactant LLPS Strategy for Sustainable and Highly Efficient Radioactive Metal Ion Separation

Advanced Science, EarlyView.
A diluent‐free, customizable liquid–liquid phase separation (LLPS) platform enables highly efficient radioactive metal ion extraction and stripping. By encapsulating hydrophobic extractants into an ionic surfactant‐rich condensed phase, this LLPS system leverages synergistic electrostatic and coordination interactions.
Ruihan Yan, Yifu Hu, Wentao Wang, Zhi Cao, Meiwen Cao, Weifang Zheng, Guoan Ye, Taihong Yan   +7 more
wiley   +1 more source

Integrated Space Geodetic Techniques For Monitoring Ground

, 2001
Ground subsidence monitoring is of paramount importance in relation to the safety and efficiency of underground mining operations. Moreover, in established coal fields in eastern Australia, it has become harder and harder to select underground minesites ...
Linlin Ge, Makoto Omura, Shigeki Kobayashi, Subsidence Due To, Chris Rizos   +4 more
core  

Genetic Code Expanded T Cell for Controllable Immunotherapy

Advanced Science, EarlyView.
Our GCE‐CAR‐T cells enables tight, dose‐dependent, and function‐preserving control of CAR expression at the translational level through amber codon suppression and genetic incorporation of ncAA. ABSTRACT Chimeric antigen receptor (CAR)‐T cell therapy has demonstrated curative potential against hematologic malignancies, but its clinical application ...
Xue Wang, Yingao Gao, Yeyu Su, Yong Wang, Tao Liu   +4 more
wiley   +1 more source

Research on deformation and failure characteristics of overburden and surface in high-intensity mining of Caojiatan Coal Mine

Meikuang Anquan
Under high-intensity mining conditions, the structural response of overburden is severe, significantly affecting the safety of surface structures. Taking the 122104 super-large mining height working face of Caojiatan Coal Mine in the Yushen Mining Area ...
Zhaolai HUA, Yang LYU, Shengxiang GAO, Zehui WU, Xufeng WANG, Lei ZHANG   +5 more
doaj   +1 more source

CK2α Deficiency Drives Myocardial Fibrosis via Desmin‐Induced Mitochondrial Dysfunction

Advanced Science, EarlyView.
CK2α preserves mitochondrial homeostasis by phosphorylating Desmin to recruit Cryab, ensuring proper filament assembly. CK2α deficiency disrupts this interaction, causing mitochondrial dysfunction, metabolic shifts, bioenergetic failure, and oxidative stress—ultimately establishing a pro‐fibrotic environment that drives cardiac fibrosis.
Canjie Ma, Jiali Jia, Juncong Lan, Jing Wang, Dan Rao, Lanlan Rao, Weibin Zhang, Dongpeng Wu, Jie Zhang, Gang Wang, Baohua Liu, Ying Ao, Zimei Wang   +12 more
wiley   +1 more source

Hybrid prediction model of surface dynamics subsidence above underground excavation

, 2022
Učinki podzemnega rudarjenja se odražajo na površini v obliki posedanja terena, kar povzroča poškodbe infrastrukture znotraj in v širšem območju rudarskega prostora.
Pal, Andrej
core  

Lighting up Macrophage Reprogramming Assists Immunosuppressive Niche Modulation in Primary Tumors and Tumor‐Draining Lymph Nodes of Breast Cancer

Advanced Science, EarlyView.
This study develops an intelligent NIR‐II‐responsive nanoplatform to combat immunosuppression in breast cancer. It enables real‐time visualization of macrophage activity via “off‐on” fluorescence while simultaneously reprogramming macrophages through the CSF‐1R and CD47‐SIRPα pathways.
Yingbo Li, Di Chang, Jie Yang, Ying Bai, Min Chen, Daoshuang Li, Zuoyu Xu, Jiaxin Yuan, Xiaoxuan Xu, Zhiqi Zhang, Yize Li, Zixin Chen, Jinbing Xie, Zebin Xiao, Shenghong Ju   +14 more
wiley   +1 more source