Results 121 to 130 of about 6,001 (279)

Time Series Analysis of Mining-Induced Subsidence Using Small Baseline Subset Interferometric Synthetic Aperture Radar (Wanli Mining Area, Inner Mongolia, China)

open access: yesApplied Sciences
The conflict between exploitation of coal resources and environmental protection is highly pronounced in the Wanli mining area, located in the arid and semi-arid region of Inner Mongolia, China.
Xinlei Xue   +5 more
doaj   +1 more source

Triple‐Negative Breast Cancer Cells Utilize IL8 and CXCL1 to Suppress NK Cells’ Function and Facilitate Cancer Metastasis

open access: yesAdvanced Science, EarlyView.
Triple‐negative breast cancer (TNBC) cells evade natural killer (NK) cell immunity by secreting IL8 and CXCL1. These chemokines suppress NK cells’ function via CXCR1/2 and enhance cancer cells’ survival through PD‐L1 upregulation and BCL‐2 anti‐apoptotic signaling.
Mingheng Yuan   +6 more
wiley   +1 more source

BCMA‐Engineered Dendritic Cell‐Derived Exosomes as Bi‐Functional Therapeutics Orchestrating Cytokine Sequestration and Immune Activation for Multiple Myeloma

open access: yesAdvanced Science, EarlyView.
A dual‐function cell‐free therapeutic based on DC2.4 cell‐derived exosomes engineered to display BCMA. (Left) Soluble Ligand Sequestration (Decoy Function): DB Exo act as molecular decoys that predominantly sequester soluble APRIL with partial BAFF attenuation, effectively disrupting the NF‐κB survival signaling axis and suppressing myeloma cell ...
Yuqing Zeng   +5 more
wiley   +1 more source

Senescent Cell Derived Artificial Vesicle‐Based Senolytic Sonovaccine Platform with Augmented Lymph Node Delivery and Antigen Cross‐Presentation Efficacy

open access: yesAdvanced Science, EarlyView.
A senolytic sonovaccine platform (SenoVac) is developed, in which senescent cell‐derived vesicles serve as broad senescent cell antigen reservior. The “2‐step” click chemistry strategy for effective lymph node delivery, and ultrasound‐triggered endosomal escape to boost cross‐presentation, ensures efficient senescent cell clearance and disease ...
Liang Zhang   +10 more
wiley   +1 more source

Dynamic prediction on goaf surface subsidence for the last two periods based on the Erf time function

open access: yesMeitian dizhi yu kantan
BackgroundThe surface subsidence induced by coal seam mining represents a continuous dynamic evolution process. Constructing a full-time perdition model for surface subsidence in goafs holds significant theoretical and practical values for the rational ...
Lianwei REN   +5 more
doaj   +1 more source

Extra Climate Benefits From Afforestation Due to Reduced Forest Fragmentation in China

open access: yesAdvanced Science, EarlyView.
Afforestation in China reduced forest fragmentation in 2015, transforming 51.8 M ha of edge forests into interior forests. This enhanced carbon sequestration (1.4±0.2 Pg CO2e, a cooling biogeochemical effect), while reduced albedo (−0.9 Pg CO2e, a warming biophysical effect) partially offset the gain, yielding a net extra climate benefit of ...
Nan Meng   +19 more
wiley   +1 more source

Surface movement monitoring and dynamic prediction system based on the optimized Knothe time function

open access: yesAIP Advances
Aiming at the engineering application problem that software development for surface subsidence prediction induced by coal mining lags behind the optimization of prediction models, this study established a dynamic prediction model for surface movement ...
Xiaojun Li, Anqi Zhu, Ruifu Yuan
doaj   +1 more source

Surface Deformation Monitoring and Subsidence Mechanism Analysis in Beijing based on Time-series InSAR [PDF]

open access: yes
This article uses 43 Sentinel-1A image datasets covering Beijing to obtain time series surface deformation information in the study area from January 2022 to October 2023.
D. Qin   +5 more
core   +1 more source

Hair Follicle Seedling Cryomicroneedles from Hierarchical Microfluidic Organoid on a Chip

open access: yesAdvanced Science, EarlyView.
In this paper, a hierarchical microfluidic chip is developed to produce uniform hair follicle organoids (HFOs) in cryomicroneedles. Cryopreservation agents encapsulate HFOs, preserving viability and hair growth potential. The cryomicroneedles enable simple intradermal transplantation with good skin penetration.
Xinyue Cao   +3 more
wiley   +1 more source

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