Results 51 to 60 of about 1,119,298 (307)

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham   +21 more
wiley   +1 more source

Surface tension of two weakly interacting liquid alloys

open access: yesBibechana, 2012
We report surface tension of two weakly segregating alloys Al-Ga and Cd-In in molten state at temperatures of 1023 K and 800 K respectively using different approaches.
RP Koirala, D Adhikari, BP Singh
doaj   +3 more sources

Smoothed Dissipative Particle Dynamics model for mesoscopic multiphase flows in the presence of thermal fluctuations

open access: yes, 2015
Thermal fluctuations cause perturbations of fluid-fluid interfaces and highly nonlinear hydrodynamics in multiphase flows. In this work, we develop a novel multiphase smoothed dissipative particle dynamics model.
Baker, Nathan A.   +5 more
core   +2 more sources

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Survismeter, 3-in-1 Instrument for Simultaneous Measurements of Surface Tension, Inter Facial Tension (IFT) and Viscosity [PDF]

open access: yesPakistan Journal of Analytical & Environmental Chemistry, 2007
The article presents Inter Facial Tension (IFT) (ift, N m-1) of benzene-water; surface tensions (, N m-1) and viscosities (, N s m-2) of ethanol, glycerol, ethyl acetate, n-hexane, diethyl ether, chloroform, benzene, carbon tetrachloride [CCl4],
Man Singh
doaj  

Surface layering of liquids: The role of surface tension

open access: yes, 2004
Recent measurements show that the free surfaces of liquid metals and alloys are always layered, regardless of composition and surface tension; a result supported by three decades of simulations and theory. Recent theoretical work claims, however, that at
A. Braslau   +39 more
core   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Surface tensions [PDF]

open access: yesCurrent Biology, 2009
SummaryA boost to the allowable catch of one EU fish population does not hide the ongoing decline of most European stocks. Nigel Williams reports.
openaire   +1 more source

Surface Tension Estimation of Steel above Boiling Temperature

open access: yesApplied Sciences
Surface tension is an important characteristic of materials. In particular at high temperatures, surface tension values are often unknown. However, for metals, these values are highly relevant in order to enable efficient industrial processing or ...
Joerg Volpp
doaj   +1 more source

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