Results 71 to 80 of about 290,884 (304)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Demo 13-19 Surface Tension Disc

, 2001
A disc connected to a limp spring is lowered onto the surface of water. When it is lifted, the surface tension of the water pulls the disc downward, causing a rather larger extension of the spring than that caused by the weight of the disc alone, as ...

core  

A method to calculate the surface tension of a cylindrical droplet

, 2010
The history of Laplace's equations for spherical and cylindrical droplets and the concept of dividing surface in Gibbs' thermodynamic theory of capillary phenomena are briefly reviewed.
Zhu RZ, 朱如曾, 王小松
core   +1 more source

Effect of Core Liquid Surface Tension on the Liquid Marble Shell

, 2020
Liquid marble is a non‐wetting droplet coated with micro‐ or nanometer sized particles and exhibits great versatility as a standalone system. Unique features such as low evaporation rate, low friction, and a porous shell enable it to be a potential tool ...
Nguyen, Nhat‐Khuong, Pradip Singha, Nhat‐Khuong Nguyen, An, Hongjie, Nam‐Trung Nguyen, Chin Hong Ooi, Sreejith, Kamalalayam Rajan, Kamalalayam Rajan Sreejith, Hongjie An, Nguyen, Nam‐Trung, Singha, Pradip, Ooi, Chin Hong   +11 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Density and Temperature Dependencies of Liquid Surface Tension [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 2011
In this paper the density and temperature dependencies of surface tension are investigated. Using the Lennard-Jones (12,6), as an effective pair interaction potential, a linear expression is derived for isotherms of g /r2  versus r2 for some normal and ...
Haniyeh Alizadeh Osgouei, Gholam Abbas Parsafar, Hamed Akbarzadeh   +2 more
doaj  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Insect-Inspired Wall-Climbing Robots Utilizing Surface Tension Forces

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2010
This paper describes insect-inspired wall-climbing robot that is capable of walking on a smooth vertical surface utilizing surface tension forces. The adhesion mechanism of the robot is inspired from the attachment system of ants, which is responsible ...
Kenji SUZUKI, Shusuke NEMOTO, Takahiro FUKUDA, Hideaki TAKANOBU, Hirofumi MIURA   +4 more
doaj   +1 more source