Results 31 to 40 of about 122,865 (312)

Surface Qualification Toolpath Optimization for Hybrid Manufacturing

Journal of Manufacturing and Materials Processing, 2021
Hybrid manufacturing machine tools have great potential to revolutionize manufacturing by combining both additive manufacturing (AM) and subtractive manufacturing (SM) processes on the same machine tool.
Austen Thien, Christopher Saldana, Thomas Kurfess   +2 more
doaj   +1 more source

Contact angle of NіTі alloy surfaces after face milling

Технічна інженерія
Wettability is an important functional property of a surface that is of fundamental importance in many fields of science and technology, from mining to biomedicine.
N.O. Balytska
doaj   +1 more source

Three-gradient regular solution model for simple liquids wetting complex surface topologies

Beilstein Journal of Nanotechnology, 2016
We use regular solution theory and implement a three-gradient model for a liquid/vapour system in contact with a complex surface topology to study the shape of a liquid drop in advancing and receding wetting scenarios.
Sabine Akerboom, Marleen Kamperman, Frans A. M. Leermakers   +2 more
doaj   +1 more source

Observation of Emergent Dirac Physics at the Surfaces of Acoustic Higher‐Order Topological Insulators

Advanced Science, 2022
Using 3D sonic crystals as acoustic higher‐order topological insulators (HOTIs), 2D surface states described by spin‐1 Dirac equations at the interfaces between the two sonic crystals with distinct topology but the same crystalline symmetry are ...
Fei Meng, Zhi‐Kang Lin, Weibai Li, Peiguang Yan, Yun Zheng, Xinping Li, Jian‐Hua Jiang, Baohua Jia, Xiaodong Huang   +8 more
doaj   +1 more source

Detailed topology mapping reveals substantial exposure of the "cytoplasmic" C-terminal tail (CTT) sequences in HIV-1 Env proteins at the cell surface. [PDF]

PLoS ONE, 2013
Substantial controversy surrounds the membrane topology of the HIV-1 gp41 C-terminal tail (CTT). While few studies have been designed to directly address the topology of the CTT, results from envelope (Env) protein trafficking studies suggest that the ...
Jonathan D Steckbeck, Chengqun Sun, Timothy J Sturgeon, Ronald C Montelaro   +3 more
doaj   +1 more source

Concurrent optimization method of shape and topology for natural vibration problem of shell structures

Nihon Kikai Gakkai ronbunshu, 2023
In this paper, a concurrent optimization method of shape and topology for natural vibration design of shell structures is presented. The fundamental vibration eigenvalue is maximized under volume constraints for shape and topology optimization.
Masatoshi SHIMODA, Ryo TSUTSUMI
doaj   +1 more source

Topology optimization of engine bracket arm using BESO

International Journal for Simulation and Multidisciplinary Design Optimization, 2023
An engine bracket is one of the most critical components of the engine used for mounting and supporting the engine in the vehicles. Today, the automobile industry requires lightweight components, which will reduce the car's overall weight when fitted ...
Srivastava Saurabh, Salunkhe Sachin, Pande Sarang   +2 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source