Results 101 to 110 of about 2,251,096 (285)

A Physically Based Spatial Expansion Algorithm for Surface Air Temperature and Humidity

Advances in Meteorology, 2013
An algorithm was developed to expand the surface air temperature and air humidity to a larger spatial domain, based on the fact that the variation of surface air temperature and air humidity is controlled jointly by the local turbulence and the ...
Hongbo Su, Jing Tian, Renhua Zhang, Shaohui Chen, Yongmin Yang, Yuan Rong, Sujuan Mi, Jianwei Qi   +7 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Reference Evapotranspiration Changes: Sensitivities to and Contributions of Meteorological Factors in the Heihe River Basin of Northwestern China (1961–2014)

Advances in Meteorology, 2016
This paper investigates reference evapotranspiration (ET0) changes, sensitivities to and contributions of meteorological factors in the Heihe River Basin (arid and inland region).
Chaoyang Du, Jingjie Yu, Ping Wang, Yichi Zhang   +3 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Reducing poverty through integrated management of groundwater and surface water

, 2014
The full poverty-fighting potential of existing irrigation schemes is not being realized?largely because of inequitable water distribution and unsustainable land and water management practices.
Global Water Partnership, International Water Management Institute   +1 more
core  

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Other title: Water Vision

, 2017
application/pdf"Kansans act on a shared commitment to have the water resources necessary to support the state's social, economic and natural resource needs for current and future generations."Vision Statement -- Surface Water Supply / Earl Lewis, Kansas ...
Kansas Water Office.
core  

Dual-Polarization Radar Quantitative Precipitation Estimation (QPE): Principles, Operations, and Challenges

Remote Sensing
Quantitative precipitation estimation (QPE) is one of the primary applications of weather radar. Over the last several decades, dual-polarization radars have significantly improved QPE accuracy by providing additional observational variables that offer ...
Zhe Zhang, Zhanfeng Zhao, Youcun Qi, Muqi Xiong   +3 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source