Results 81 to 90 of about 5,049,215 (291)

Environmental flow assessment, evaluation, and suggestions for dying riverine ecosystem of the transboundary Amudarya River, Central Asia

Ecological Indicators
The Amudarya River (ADR) is the largest source of freshwater in Central Asia providing livelihood to millions of people by extracting water for agriculture. However, the over-exploitation has created some critical environmental issues.
Rashid Mahmood, Shaofeng Jia, Aifeng Lv, Shahid Naeem   +3 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Review of Research on the Present Situation of Development and Resource Potential of Wind and Solar Energy in China

Energies
To address the global warming issue, China is prioritizing the development of clean energy sources such as wind and solar power under its “dual carbon target”.
Taohui Li, Yonghao Liu, Aifeng Lv
doaj   +1 more source

Study on the Variation of Terrestrial Water Storage and the Identification of Its Relationship with Hydrological Cycle Factors in the Tarim River Basin, China

Advances in Meteorology, 2017
The terrestrial water storage anomalies (TWSAs) in the Tarim River Basin (TRB) were investigated and the related factors of water variations in the mountain areas were analyzed based on Gravity Recovery and Climate Experiment (GRACE) data, in situ river ...
Peng Yang, Jun Xia, Chesheng Zhan, Yongyong Zhang, Jie Chen   +4 more
doaj   +1 more source

Role of Rotations on Surface Diffusion of Water Trimers on Pd\{111\} [PDF]

, 2016
Diffusion barriers for a cluster of three water molecules on Pd(111) have been estimated from ab-initio Density Functional Theory. A model for the diffusion of the trimer based in rotations yields a simple explanation of why the cluster can diffuse ...
de Andres, P. L., Ranea, Victor A.
core   +3 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Surface waters

Eos, Transactions American Geophysical Union, 1971
Much recent progress in predicting surface water flows from natural watersheds for engineering purposes has been stimulated by the advent of the computer and the various theories of systems modeling, common nowadays to all branches of the physical and biological sciences.
openaire   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

A global drought dataset for Multivariate Composite Drought Index (MCDI) and its constituent drought indices

Scientific Data
High-resolution drought index datasets are essential for drought monitoring and assessment. Despite numerous global/regional drought index datasets, the composite drought index datasets that comprehensively consider meteorological, agricultural, and ...
Mengjia Yuan, Guojing Gan, Jingyi Bu, Yanxin Su, Hongyu Ma, Xianghe Liu, Leyao Zhang, Yongqiang Zhang, Yanchun Gao   +8 more
doaj   +1 more source