Results 81 to 90 of about 1,775,266 (219)

Dual-Polarization Radar Quantitative Precipitation Estimation (QPE): Principles, Operations, and Challenges

open access: yesRemote Sensing
Quantitative precipitation estimation (QPE) is one of the primary applications of weather radar. Over the last several decades, dual-polarization radars have significantly improved QPE accuracy by providing additional observational variables that offer ...
Zhe Zhang   +3 more
doaj   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

open access: yesFEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno   +3 more
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Decomposing the Effects of Changes in Catchment Characteristics on Runoff Into Chain Transmission Effects of Climate Change and Human Activities Using an Improved Budyko Framework

open access: yesEarth's Future
Effect of catchment characteristics (e.g., land use/land cover changes) is increasingly accepted as the main cause of runoff changes, besides direct effects of climate change and human activities.
Kun Peng   +6 more
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

Exploring the influence of lactoferrin on wound healing and related signaling pathways: a systematic review

open access: yesFEBS Open Bio, EarlyView.
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo   +4 more
wiley   +1 more source

Enlarging Difference Between Persistent Extreme Precipitation and Fixed‐Time Extremes in China

open access: yesEarth's Future
Extreme precipitation occurs persistently in nature and has caused a series of social, environmental, and ecological problems. However, most analyses of extreme precipitation are conducted at fixed‐time intervals, which may lead to misconceptions of the ...
Yihui Zhang   +3 more
doaj   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

open access: yesFEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow   +12 more
wiley   +1 more source

Declining Contribution of Plant Physiological Effects to Global Drought Characteristics With Rising CO2 Using State‐of‐the‐Art Earth System Models

open access: yesEarth's Future
Vegetation physiology responses to rising atmospheric CO2 can alter the global hydrological cycle, thereby influencing drought occurrence. It has long been controversial and poorly understood how vegetation physiological effects influence meteorological ...
Ziwei Li   +3 more
doaj   +1 more source

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