Results 71 to 80 of about 247,498 (307)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Effects of the Oxidation/Reduction Potential on Sediment Ammonia Release in Surface Waters [PDF]

, 2016
In recent years, rapid urbanization and agricultural intensification have led to widespread nutrient enrichment of surface waters. From this nutrients, ammonia, a common nitrogen species, is of great concern because it exacerbates the proliferation of ...
Waters, Edward
core  

Using automatic calibration to improve the physics behind complex numerical models: an example from a 3D lake model using Delft3D (v6.02.10) and DYNO-PODS (v1.0) [PDF]

Geoscientific Model Development
Models are simplified descriptions of reality and are intrinsically limited by the assumptions that have been introduced in their formulation. With the development of automatic calibration toolboxes, finding optimal parameters that suit the environmental
M. Amadori, M. Amadori, A. Irani Rahaghi, A. Irani Rahaghi, D. Bouffard, D. Bouffard, M. Toffolon   +6 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Eastern Mediterranean surface water temperatures and d18O composition during deposition of sapropels in the late Quaternary [PDF]

, 2003
Water column stratification increased at climatic transitions from cold to warm periods during the lateQuaternary and led to anoxic conditions and sapropel formation in the deep eastern Mediterranean basins.
Struck, U., Erlenkeuser, H., Emeis, K.C., Rossignol-Strick, M., Howell, M. W., Emeis, K.-C., Oba, T., Kroon, Dirk, Schulz, H., Kroon, D., Mackensen, Andreas, Sakamoto, T., Emeis, K. C., Koizumi, I., Ishizuka, S., Mackensen, A., Howell, M.W.   +16 more
core   +1 more source

Lacustrine Groundwater Discharge Through Giant Pockmarks (Lake Neuchatel, Switzerland)

Frontiers in Water, 2020
Pockmarks are circular depressions on the floor of oceans and lakes and constitute potential hot spots of gas ebullition and/or groundwater discharge. Marine pockmarks are well-studied, whereas lacustrine pockmarks are virtually unexplored.
Stefanie B. Wirth, Damien Bouffard, Jakob Zopfi   +2 more
doaj   +1 more source

Late Holocene Climate Changes in the Altai Region Based on a First High‐Resolution Biomarker Isotope Record From Lake Khar Nuur

Geophysical Research Letters, 2021
The Late Holocene marks a substantial cultural and economic transition in the eastern Eurasian Steppe and Altai Region with the dispersal of nomadic pastoralism. So far, paleoclimate conditions during this time remain unclear and controversial.
Marcel Bliedtner, Julian Struck, Paul Strobel, Gary Salazar, Sönke Szidat, Enkhtuya Bazarradnaa, Ronald Lloren, Nathalie Dubois, Roland Zech   +8 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Tin contamination in sediments of Lake Zurich: source, spread, history and risk assessment

Swiss Journal of Geosciences
Industrial activities of a silk dyeing factory in Thalwil, on the shore of Lake Zurich, Switzerland, caused extreme Sn contamination of lake sediments. In this study, we determine the contamination source, spread, and age using a multiproxy approach.
Remo L. Roethlin, Aurélia C. E. Meister, Adrian Gilli, Sinikka T. Lennartz, Helen Eri Amsler, Maria Dittrich, Bernhard Wehrli, Maria Schönbächler, Nathalie Dubois   +8 more
doaj   +1 more source

Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach

FEBS Letters, EarlyView.
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring, Jan de Jonge, Hans‐Peter Braun, Nils Rugen   +3 more
wiley   +1 more source