Results 111 to 120 of about 119,289,483 (303)

Effective in vivo treatment of acute lung injury with helical, amphipathic peptoid mimics of pulmonary surfactant proteins

Scientific Reports, 2018
Acute lung injury (ALI) leads to progressive loss of breathing capacity and hypoxemia, as well as pulmonary surfactant dysfunction. ALI’s pathogenesis and management are complex, and it is a significant cause of morbidity and mortality worldwide ...
Ann M. Czyzewski, Lynda M. McCaig, Michelle T. Dohm, Lauren A. Broering, Li-Juan Yao, Nathan J. Brown, Maruti K. Didwania, Jennifer S. Lin, Jim F. Lewis, Ruud Veldhuizen, Annelise E. Barron   +10 more
doaj   +1 more source

In Situ Interfacial Assembly of Dynamic Semi‐Interpenetrating Biopolymer Networks for Robust and Mechanically Adaptive Droplet Interfaces

Advanced Functional Materials, EarlyView.
A dynamic interfacial semi‐interpenetrating polymer network is constructed by sequential assembly of β‐sheet‐rich SF and CS‐RL. The SF framework provides mechanical strength, while dynamically associated CS‐RL enables local rearrangement, allowing droplets to rapidly reconfigure without loss of interfacial integrity.
Yaping Zhang, Yujie Liu, Yikai Xu, Xunda Feng, Ling Zhang, Hongbo Zeng, Hao Liu, Xiaohui Mao   +7 more
wiley   +1 more source

Animal characteristics, protein secretion, and surfactant levels.

, 2016
Animal characteristics, protein secretion, and surfactant levels.
Emily Royse (3146850), Noah H. Hillman (556724), Rebecca Y. Petersen (3146853), Matthew W. Kemp (320771), Alan H. Jobe (320777), Yuichiro Miura (665020), Andres Noe (3146847)   +6 more
core   +1 more source

Relationship between plasma SP-A expression level and disease stage in silicosis patients

Shanghai yufang yixue
ObjectiveTo investigate the relationship between plasma surfactant protein⁃A （SP⁃A） expression level and silicosis progression， and to provide early evidence for exploring whether SP⁃A can be used as a biomarker for clinical monitoring of silicosis ...
CHEN Kengkeng, ZHANG Bizhu, PENG Yingyi, LIU Zhifang, CHEN Xiaoyan, JIN Jiachun   +5 more
doaj   +1 more source

Endosomal Escape of siRNA Polyplexes: A Molecular Dynamics Perspective on Underlying Mechanisms

Advanced Functional Materials, EarlyView.
Molecular dynamics simulations reveal distinct endosomal escape mechanisms of siRNA nanoparticles, ranging from electrostatic membrane attachment to hydrophobic membrane fusion. Hydrophobic residues and anionic endosomal lipids emerge as key determinants of membrane disruption, linking molecular interactions to experimental delivery performance and ...
Katharina M. Steinegger, Min Jiang, Florian Belger, Fabian Link, Benjamin Winkeljann, Olivia M. Merkel   +5 more
wiley   +1 more source

Methylprednisolone regulation of human donor lung surfactant protein A (SP-A) expression is dependent on the SP-A polymorphism.

, 2012
Methylprednisolone regulation of human donor lung surfactant protein A (SP-A) expression is dependent on the SP-A ...
Kim C, Floros J, DiAngelo S, Aramini B, Sonett J and D'Ovidio F., Costa J, Arcasoy S, Lederer D   +7 more
core   +1 more source

Architectural Tuning of Bouligand Electrospun Laminates Enables Coupled Mechanical Robustness and Electromechanical Sensing

Advanced Functional Materials, EarlyView.
Bioinspired Bouligand architectures are translated into biodegradable polymer laminates with integrated sensing, revealing how structural design governs multifunctional performance. A 20° interlayer rotation optimizes strength, flexibility, and electromechanical response, while embedded nanotube networks enable real‐time damage detection and wearable ...
Piotr K. Szewczyk, Daniel P. Ura, Michał Kopacz, Katarzyna Marszalik, Urszula Stachewicz   +4 more
wiley   +1 more source

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

Advanced Healthcare Materials, EarlyView.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj, Xilal Y. Rima, Kim T. Nguyen, Courtney Culkins, Nana Boateng, Jacob Doon‐Ralls, Alejandro Bresolin, Xin Huang, Hong Li, Vahedi Amid, Ajeet Pal Singh, Dharti Shantaram, Anastasiia Amari, Mangesh D. Hade, Nicholas R. Merriam, Zachary D. Schultz, Scott Q. Harper, Nizar Y. Saad, Setty M. Magaña, Willa A. Hsueh, Rachel E. Kopec, Blaise R. Kimmel, Andre F. Palmer, Eduardo Reátegui   +23 more
wiley   +1 more source

Rheological Properties of Protein-Surfactant based gels

, 2005
Water-based protein-surfactant gels, formed by mixing bovine serum albumin (BSA) and sodium dodecyl sulfate in water, were investigated by rheological methods.
ROVERSI M, LA MESA, Camillo
core   +1 more source

Prostate Cancer Patient‐Derived Organoids (PDOs) as Functional Avatars for Antisense Oligonucleotide (ASO)‐Based Personalized Therapy

Advanced Healthcare Materials, EarlyView.
Prostate patient‐derived organoids (PDOs) were established from TURP and biopsy specimens with >90% success and retain key features of their tissues of origin, making them functional avatars for antisense oligonucleotide (ASO) therapy . Transfecting single cells outside the Matrigel matrix and then reconstituting organoids overcomes the 3D delivery ...
Thi Thom Tran, Thi Tu Uyen Phan, Michael Baboudjian, Quang Hieu Duong, Ines Sousa, Thi Thuy Le, Virginie Baylot, Sophie Giusiano, Laurent Daniel, Pauline Brige, Benjamin Guillet, Cyrille Bastide, Carmen Garrido, David Taïeb, Thi Khanh Le, Palma Rocchi   +15 more
wiley   +1 more source