Results 61 to 70 of about 119,289,483 (303)

The Potential Role of Bioactive Plasmalogens in Lung Surfactant

Frontiers in Cell and Developmental Biology, 2021
Neonatal respiratory distress syndrome (NRDS) is a type of newborn disorder caused by the deficiency or late appearance of lung surfactant, a mixture of lipids and proteins.
Ruijiang Zhuo, Pu Rong, Jieli Wang, Rokshana Parvin, Yuru Deng, Yuru Deng   +5 more
doaj   +1 more source

Human surfactant protein D alters oxidative stress and HMGA1 expression to induce p53 apoptotic pathway in eosinophil leukemic cell line [PDF]

, 2013
This article is made available through the Brunel Open Access Publishing Fund. Copyright: © 2013 Mahajan et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use ...
Pandit Hrishikesh, Uday Kishore (504246), Ravi Sirdeshmukh, P. Usha Sarma (504245), Curam S Sundaram, Lakshna Mahajan (504239), Madan, T, Ajit K Yadav, Madan Taruna, Poonam Gautam, Ajit K. Yadav (504242), Curam S. Sundaram (504244), Yadav Ajit K., Ravi Sirdeshmukh (131378), Himangi Warke, P. Usha Sarma, Surolia Avadhesha, Warke Himangi, Lakshna Mahajan, Hrishikesh Pandit, Pandit, H, Sundaram, CS, Himangi Warke (504243), Sarma, PU, Poonam Gautam (131332), Sundaram Curam S., Sirdeshmukh Ravi, Sarma P. Usha, Surolia, A, Curam S. Sundaram, Avadhesha Surolia (78297), Mahajan, L, Kishore Uday, Yadav, AK, Sirdeshmukh, R, Warke, H, Taruna Madan, Kishore, U, Taruna Madan (504241), P Usha Sarma, Gautam, P, Mahajan Lakshna, Gautam Poonam, Hrishikesh Pandit (504240), Ajit K. Yadav, Avadhesha Surolia, Uday Kishore   +46 more
core   +2 more sources

Simulation of dynamics of adsorption of mixed protein-surfactant on a bubble surface

, 2013
The dynamics of adsorption of mixed protein–surfactant on a bubble surface is simulated mathematically. The model for the adsorption dynamics is developed based on the Ward–Tordai equation combined with the Frumkin adsorption isotherm.
Grassia, Paul, Vitasari, Denny, Martin, Peter, Martin, Peter; id_orcid   +3 more
core   +3 more sources

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Human decidua-derived mesenchymal stem cells differentiate into functional alveolar type II-like cells that synthesize and secrete pulmonary surfactant complexes. [PDF]

PLoS ONE, 2014
Lung alveolar type II (ATII) cells are specialized in the synthesis and secretion of pulmonary surfactant, a lipid-protein complex that reduces surface tension to minimize the work of breathing.
Alejandro Cerrada, Paz de la Torre, Jesús Grande, Thomas Haller, Ana I Flores, Jesús Pérez-Gil   +5 more
doaj   +1 more source

Surfactant protein metabolism in vivo

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 1998
The surfactant components saturated phosphatidylcholine, SP-B and SP-C, are secreted together in lamellar bodies, and at least a part of the de novo synthesized SP-A is secreted independently. The surface film forms from tubular myelin and loose lipid arrays, and it generates unilamellar vesicles that lack surfactant proteins and are thought to ...
Ikegami, Machiko, Jobe, Alan H.
openaire   +2 more sources

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

Association of Single Nucleotide Polymorphisms in Surfactant Protein A and D with Otitis Media. [PDF]

, 2007
Otitis Media is one of the most common childhood diseases. Recurrent acute otitis media RAOM is characterized by repeated episodes of inflammation of the middle ear in conjunction with middle ear fluid, and often with an inflamed or bulging eardrum ...
Barnett, Catherine Margaret Eleanor
core  

A minimal cellulosome‐like system in Cellulosilyticum lentocellum

FEBS Open Bio, EarlyView.
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan, Amias Alstrom‐Moore, Gary W Black   +2 more
wiley   +1 more source

New surfactant with SP-B and C analogs gives survival benefit after inactivation in preterm lambs. [PDF]

PLoS ONE, 2012
BACKGROUND: Respiratory distress syndrome in preterm babies is caused by a pulmonary surfactant deficiency, but also by its inactivation due to various conditions, including plasma protein leakage.
Matthias Seehase, Jennifer J P Collins, Elke Kuypers, Reint K Jellema, Daan R M G Ophelders, Olga L Ospina, J Perez-Gil, Federico Bianco, Raffaella Garzia, Roberta Razzetti, Boris W Kramer   +10 more
doaj   +1 more source