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Surfactin variants for intra-intestinal delivery of insulin

European Journal of Pharmaceutics and Biopharmaceutics, 2017
Surfactin is a Bacillus-produced natural lipopeptide, which can overcome the epithelial cell barriers for orally delivering insulin, but its ability to promote uptake of insulin by the intestine need to be further improved for a higher oral bioavailability.
Li, Zhang   +4 more
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Toxicity and applications of surfactin for health and environmental biotechnology

Journal of Toxicology and Environmental Health, Part B, 2018
Characterized as one of the most potent biosurfactants, surfactin is a cyclic lipopeptide synthesized by several strains of Bacillus genus. The aim of this review was to present the physicochemical and structural properties of surfactin and to demonstrate advances and applications of this biosurfactant for health and environmental biotechnology ...
Vanessa Santana Vieira, Santos   +2 more
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Surfactin Activity Depends on the Membrane Dipole Potential

Langmuir, 2010
The effect of dipole modifying agents phloretin and RH 421 on the membrane conductance induced by surfactin, a lipopeptide antibiotic from Bacillus subtilis, was studied. Surfactin added on both sides of a bilayer formed from diphytanoylphosphocholine in 1 M KCl (pH 6.5) leads to the formation of voltage-independent channels of different conductance ...
Olga S, Ostroumova   +3 more
openaire   +2 more sources

Characterization of the surfactin synthetase multi-enzyme complex

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, 1994
Three subunits (srfAORF1, srfAORF2 and srfAORF3) of the Bacillus subtilis surfactin synthetase multi-enzyme complex have been identified by SDS-PAGE and Western blot analyses. In accordance with the sequence analysis of the surfactin (srfA) operon, the protein subunits have a molecular mass of 402,000 Da, 401,000 Da and 144,000 Da, respectively ...
G, Galli   +6 more
openaire   +2 more sources

Surfactin: Biosynthesis, Genetics and Potential Applications

2010
Even after forty years of its discovery by Arima et al, surfactin, a potent lipopeptide biosurfactant, still attracts attention and fancy of the applied microbiologists and biotechnologists worldwide, mainly due to its versatile bioactive properties and potential industrial implications.
openaire   +2 more sources

The production of surfactin by Bacillus subtilis /

1985
This item was digitized as part of a project to share McGill's intellectual legacy with the public. If you are the copyright holder or a relative of the copyright holder who is deceased, you may request withdrawal by emailing escholarship.library@mcgill.ca.
openaire   +1 more source

[Isolation and identification of surfactin producing Bacillus subtilis strain and its effect of surfactin on crude oil].

Wei sheng wu xue bao = Acta microbiologica Sinica, 2009
Strains producing biological surfactants were isolated from formation water of Daqing oil field, Heilongjiang Province, China. From which a lipopeptide producing strain ZW-3 was screened out by PCR of the sfp gene. The morphology, cultural characteristics, physiological, biochemical properties and chemotaxonomy of strain ZW-3 were studied.
Dawei, Wang   +4 more
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Surfactin and Other Lipopeptides from Bacillus spp.

2010
Isolated during 1950s and 1960s, the group of lipopeptides from Bacillus spp. gather more than 30 different peptides linked to various fatty acid chains. More than a 100 different compounds can so be described. In this chapter, they are classified into four main families: the surfactins, the iturins, the fengycins or plipastatins and the kurstakins ...
openaire   +2 more sources

MICELLAR CHARACTERISTICS OF THE BIOLOGICAL SURFACTANT - SURFACTIN

Herald of Technological University
Biological surfactants produced by bacteria and living organisms are used in the food, agricultural, pharmaceutical and medical, cosmetic, oil and gas industries, for soil remediation, and purification of industrial wastewater. They are highly biodegradable, low toxic, low cost, and are a "green" alternative to synthetic surfactants. The paper presents
V.P. ARKHIPOV, N.A. KUZINA, YA.V. IVSHIN
openaire   +1 more source

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