Results 1 to 10 of about 7,932,048 (422)

Repression of the stress granule protein G3BP2 inhibits immune checkpoint molecule PD‐L1

open access: yesMolecular Oncology, EarlyView., 2022
Mounting evidence suggests that cancer stemness and immunosuppression are related, but the underlying mechanisms are not clear. We previously reported that the stress granule‐associated protein G3BP2 is involved in regulating tumor‐initiating (stem) cells.
Yanhong Zhang   +3 more
wiley   +1 more source

Metabolism and signaling crosstalk in glioblastoma progression and therapy resistance

open access: yesMolecular Oncology, EarlyView., 2023
Glioblastoma is one of the most lethal human cancers with no effective treatment nowadays. Here, we review the increasing amount of evidence supporting the connection between cell signaling deregulation and metabolic reprogramming as a key event in glioblastoma resistance to cancer therapy.
Laura Zarzuela   +2 more
wiley   +1 more source

Safely Implementing a Program of Pure Laparoscopic Donor Right Hepatectomy: The Experience From a Southeast Asian Center

open access: yesTransplantation Direct, 2023
Background:. Laparoscopic donor right hepatectomy (LDRH) is a technically challenging procedure. There is increasing evidence demonstrating the safety of LDRH in high-volume expert centers.
Jia-Hao Law, MMed (Surgery)   +8 more
doaj   +1 more source

Guidelines for Perioperative Pain Management in Total Knee Arthroplasty in China (2022)

open access: yesXiehe Yixue Zazhi, 2022
Total knee arthroplasty (TKA) is currently the main treatment for end-stage knee disease. Moderate to severe pain often occurs after TKA, which seriously affects postoperative rehabilitation, patient satisfaction and overall outcome. Multimodal analgesia
Joint Surgery Branch of Chinese Orthopaedic Association   +1 more
doaj   +1 more source

Perioperative chemotherapy versus surgery alone for resectable gastroesophageal cancer.

open access: yesNew England Journal of Medicine, 2006
BACKGROUND A regimen of epirubicin, cisplatin, and infused fluorouracil (ECF) improves survival among patients with incurable locally advanced or metastatic gastric adenocarcinoma.
D. Cunningham   +15 more
semanticscholar   +1 more source

Short- to Medium-term Outcome of Prepectoral versus Subpectoral Direct-to-implant Reconstruction using Acellular Dermal Matrix

open access: yesPlastic and Reconstructive Surgery, Global Open, 2021
Background:. Subpectoral implant reconstruction (SIR) is associated with animation deformity and increased postoperative pain. The aim of our study was to compare the short- to medium-term outcome of prepectoral implant reconstruction (PIR) and SIR with ...
John Mathew, MS, FRCS, DM, FRCS (Surgery)
doaj   +1 more source

10-Year Outcomes after Monitoring, Surgery, or Radiotherapy for Localized Prostate Cancer.

open access: yesNew England Journal of Medicine, 2017
BACKGROUND The comparative effectiveness of treatments for prostate cancer that is detected by prostate-specific antigen (PSA) testing remains uncertain.
F. Hamdy   +26 more
semanticscholar   +1 more source

Minimally Invasive Surgery and the Novel Coronavirus Outbreak: Lessons Learned in China and Italy

open access: yesAnnals of Surgery, 2020
Min Hua Zheng 1 MD, Luigi Boni 2 MD FACS, Abe Fingerhut 1,3 MD FACS 1 Department of General Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Minimally Invasive Surgery Center, Shanghai 200025, P. R.
M. Zheng, L. Boni, A. Fingerhut
semanticscholar   +1 more source

Heegaard Floer homology and chirally cosmetic surgeries [PDF]

open access: yes, 2021
A pair of surgeries on a knot is chirally cosmetic if they result in homeomorphic manifolds with opposite orientations. We find new obstructions to the existence of such surgeries coming from Heegaard Floer homology; in particular, we make use of immersed curve formulations of knot Floer homology and the corresponding surgery formula. As an application,
arxiv   +1 more source

Effects of bariatric surgery on mortality in Swedish obese subjects.

open access: yesNew England Journal of Medicine, 2007
BACKGROUND Obesity is associated with increased mortality. Weight loss improves cardiovascular risk factors, but no prospective interventional studies have reported whether weight loss decreases overall mortality.
L. Sjöström   +22 more
semanticscholar   +1 more source

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