Results 91 to 100 of about 364,260 (304)

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Kidney volume measurement and predictive modeling in children aged 0–18 years using a computer-assisted surgery system

open access: yesScientific Reports
This study aimed to measure the normal renal volume in children and adolescents aged 0–18 years from the eastern coastal region of China using the computer-assisted surgery (CAS) system.
Yao Liu   +11 more
doaj   +1 more source

Accuracy of computer-assisted surgery in mandibular reconstruction: A postoperative evaluation guideline.

open access: yesOral Oncology, 2019
Comparing accuracy results for mandibular reconstructions using computer-assisted surgery (CAS) is limited due to heterogeneity in image acquisition, extent of mandibular resection, and evaluation methodologies between studies.
G. V. van Baar   +4 more
semanticscholar   +1 more source

Techniques for Computer Assisted Surgery

open access: yes, 2007
In the recent decades robotic and computer science have been gaining more and more relevance in all aspects of our lives. In surgery, for example, they gave birth to procedures that would be impossible to perform otherwise (e.g. tele-surgery, nano-surgery).
Turini G   +3 more
openaire   +3 more sources

Digital Cognitive Phenotyping for Differential Diagnosis and Monitoring in Neurological Conditions

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To assess the utility, accessibility, and equivalence to supervised scales of online cognitive assessment in older individuals with cognitive impairment. Methods Patients with Alzheimer's disease (AD, n = 31), idiopathic normal pressure hydrocephalus (iNPH, n = 26), and traumatic brain injury (TBI, n = 23) completed online cognitive ...
Martina Del Giovane   +10 more
wiley   +1 more source

Blood RNA Biomarker Signatures for Early Diagnosis and Prognosis in Ischemic and Hemorrhagic Stroke: The IBIS‐CT1 Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau   +11 more
wiley   +1 more source

Development of an Assistance System for the Intuitive Assessment of Laboratory Findings in Oncology

open access: yesCurrent Directions in Biomedical Engineering, 2019
Due to the broad spectrum of individual functionalities, current hospital information systems in most cases do not offer quick information access or proper assistance in information assessment.
Oeser Alexander   +2 more
doaj   +1 more source

Impact of Age on the Diagnostic Yield of Routine EEG in People With Childhood or Juvenile Absence Epilepsy: A Cross‐Sectional Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background We aimed to identify the proportion of individuals with a confirmed diagnosis of childhood absence epilepsy (CAE) or juvenile absence epilepsy (JAE) who show a negative routine EEG (rEEG), and to determine the main factors associated with this finding.
Francesco Fortunato   +7 more
wiley   +1 more source

Hybrid polymer vessel phantoms for feasibility studies and clinical training of MRI-guided interventions

open access: yesCurrent Directions in Biomedical Engineering, 2022
Gholami Bajestani Denis   +4 more
doaj   +1 more source

Requirements elicitation for robotic and computer-assisted minimally invasive surgery

open access: yesInternational Journal of Advanced Robotic Systems, 2019
The robotic surgical systems and computer-assisted technologies market has seen impressive growth over the last decades, but uptake by end-users is still scarce.
H. Nakawala   +14 more
semanticscholar   +1 more source

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