Results 71 to 80 of about 116,145 (312)

ADVANCED IMAGING AND COMPUTER-ASSISTED SURGERY OF THE KNEE AND HIP Introduction

open access: yes, 2009
The 2008 American Academy of Orthopaedic Surgeons/Orthopaedic Research Society Advanced Imaging and Computer-Assisted Surgery of the Knee and Hip (AICKH) Research Symposium created a forum for the collaboration of experts from multiple disciplines to ...
Gray, Martha L., Pearle, Andrew D.
core   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Comparison of spectral characteristics in human and pig biliary system with hyperspectral imaging (HSI)

open access: yesCurrent Directions in Biomedical Engineering, 2020
Injuries to the biliary tree during surgical, endoscopic or invasive radiological diagnostic or therapeutic procedures involving the pancreas, liver or organs of the upper gastrointestinal tract give rise to the need to develop a method for clear ...
Cooney Gary Sean   +5 more
doaj   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

Recognition of the lumbar spine using MRI plane-based FiLM conditioning and patient dependent batching on semantic segmentation

open access: yesCurrent Directions in Biomedical Engineering
Lower back pain (LBP) is a common symptom that can be linked to the degeneration of intervertebral discs or injuries to vertebrae. Accurate segmentation of lumbar spinal structures is vital for image-based surgery planning but can be resource intensive ...
Stelzner Tim   +7 more
doaj   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

open access: yesFEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes   +32 more
wiley   +1 more source

Tumour surgery: Bone cuttings using saw guides

open access: yes, 2012
Primary malignant bone tumor often requires a surgical treatment to remove the tumor and sometimes restore the anatomy using a frozen allograft. During the removal, there is a need for a highest possible accuracy to obtain a wide safe margin from the ...
Cartiaux, Olivier   +5 more
core  

Registration accuracy in computer-assisted pelvic surgery

open access: yes, 2009
Introduction: An in vitro study was performed to assess the global registration accuracy of a computer-assisted system in pelvic orthopaedic surgery. The system was applied to a putative tumor resection in a pelvic sawbone. Methods: Twenty landmarks were
Cartiaux, Olivier   +7 more
core   +1 more source

Automatic depth scanning system for 3D infrared thermography

open access: yesCurrent Directions in Biomedical Engineering, 2016
Infrared thermography can be used as a pre-, intra- and post-operative imaging technique during medical treatment of patients. Modern infrared thermal cameras are capable of acquiring images with a high sensitivity of 10 mK and beyond.
Unger Michael   +2 more
doaj   +1 more source

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