Results 61 to 70 of about 116,145 (312)

Virtual Cranio-Maxillofacial Surgery Planning with Stereo Graphics and Haptics

, 2016
Computer-Assisted Surgery (CAS) is a new tool for performing complex procedures in a predictable and safe way. This book is designed to serve as a comprehensive review of Computer-Assisted Surgery, covering the current status of both research and ...
Malmberg, Filip,, Seipel, Stefan,, Nyström, Ingela,, Olsson, Pontus,, Nysjö, Fredrik,, Hirsch, Jan Michael,, Nysjö, Johan,, Carlbom, Ingrid B,   +7 more
core   +1 more source

Towards structuring contextual information for workflow-driven surgical assistance functionalities

Current Directions in Biomedical Engineering, 2015
A workflow-driven cooperative working environment needs to be established in order to successfully unburden the surgeon and the OR staff from technical configuration and information-seeking tasks.
Franke Stefan, Neumuth Thomas
doaj   +1 more source

Towards a framework for standardized semantic workflow modeling and management in the surgical domain

Current Directions in Biomedical Engineering, 2015
An essential aspect for workflow management support in operating room environments is the description and visualization of the underlying processes and activities in a machine readable format as Surgical Process Models (SPM).
Neumann Juliane, Neumuth Thomas
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Robot assisted Internal Mammary Artery detection for coronary revascularisation surgery

, 2010
This paper presents a semi-automatic robotic system supporting a surgeon in the harvesting of the internal mammary artery (IMA) for an open chested intervention in coronary revascularisation surgery.
Vazquez, Adrian, Hirzinger, Gerd, Florian A Fröhlich, Passig, Georg, Georg Passig, Gerd Hirzinger, Adrian Vazquez, Fröhlich, Florian A.   +7 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Computer-assisted surgery for subtalar arthrodesis

, 2008
Background: Despite considerable recent interest in computer navigation for orthopaedic surgery, few investigations of computer-assisted surgery for foot and ankle operations have been reported.
Ogut, Tahir, Easley, Mark, Cooperman, Nathan, Reach, John, Schuh, Reinhard, Chuckpaiwong, Bavornrit, Le, Ian L. D.   +6 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Requirement Analysis for an Aerial Relay in Emergency Response Missions

Current Directions in Biomedical Engineering, 2020
First aid of patients at the scene of an emergency requires an adequate flow of information. The publicly funded research project MOMENTUM aims at seamlessly connecting the point of care to the hospital.
Gruner Jonas, Bloße Albrecht, Rockstroh Max, Neumuth Thomas, Rostalski Philipp   +4 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source