Results 51 to 60 of about 64,040 (222)

Establishment and biological characterization of radioresistant colorectal cancer cell lines

FEBS Open Bio, EarlyView.
Under ionizing radiation exposure, radiation‐sensitive cancer cells exhibit oxidative stress and DNA damage, while radiation‐resistant cancer cells exhibit strong antioxidant properties and DNA damage repair. Radiotherapy resistance is a major cause of recurrence and metastasis in colorectal cancer (CRC).
Tian‐Yin Qu, Qing Dai, Jing Leng, Lin Fang, Jing‐Jing Ma, Rui Chen, Che Chen, Peng‐Fei Ran, Wen‐Wen Zhou, Chang Liu, Huang‐Fei Yu   +10 more
wiley   +1 more source

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source

Networking Seifert Surgeries on Knots IV: Seiferters and branched coverings [PDF]

arXiv, 2012
A Seifert surgery is an integral surgery on a knot in S^3 producing a Seifert fiber space which may contain an exceptional fiber of index 0. The Seifert Surgery Network is a 1-dimensional complex whose vertices correspond to Seifert surgeries; its edges correspond to single twistings along "seiferters" or "annular pairs of seiferters".
arxiv  

Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies

Aging and Cancer, EarlyView.
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal, Abhimanyu Chiraparambil Radhakrishnan, Ayanchetty Haripraba, Saif Syed, Gajawada Pragna, Ayush Dwivedi, Akash Rawat, Daniela Castro Calderón, Martin Cevallos‐Cueva   +8 more
wiley   +1 more source

Neighbors of Seifert surgeries on a trefoil knot in the Seifert Surgery Network [PDF]

arXiv, 2014
A Seifert surgery is a pair (K, m) of a knot K in the 3-sphere and an integer m such that m-Dehn surgery on K results in a Seifert fiber space allowed to contain fibers of index zero. Twisting K along a trivial knot called a seiferter for (K, m) yields Seifert surgeries. We study Seifert surgeries obtained from those on a trefoil knot by twisting along
arxiv  

Quantum computing by color-code lattice surgery [PDF]

arXiv, 2014
We demonstrate how to use lattice surgery to enact a universal set of fault-tolerant quantum operations with color codes. Along the way, we also improve existing surface-code lattice-surgery methods. Lattice-surgery methods use fewer qubits and the same time or less than associated defect-braiding methods.
arxiv  

Does dose calculation algorithm affect the dosimetric accuracy of synthetic CT for MR‐only radiotherapy planning in brain tumors?

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose This study compares the dosimetric accuracy of deep‐learning‐based MR synthetic CT (sCT) in brain radiotherapy between the Analytical Anisotropic Algorithm (AAA) and AcurosXB (AXB). Additionally, it proposes a novel metric to predict the dosimetric accuracy of sCT for individual post‐surgical brain cases.
Jeffrey C. F. Lui, Francis K. H. Lee, C. C. Law, James C. H. Chow   +3 more
wiley   +1 more source

T2‐weighted imaging of rectal cancer using a 3D fast spin echo sequence with and without deep learning reconstruction: A reader study

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose To compare image quality and clinical utility of a T2‐weighted (T2W) 3‐dimensional (3D) fast spin echo (FSE) sequence using deep learning reconstruction (DLR) versus conventional reconstruction for rectal magnetic resonance imaging (MRI).
Dan Nguyen, Sarah Palmquist, Ken‐Pin Hwang, Jingfei Ma, Usama Salem, Jia Sun, Xinzeng Wang, Jong Bum Son, Randy Ernst, Peng Wei, Harmeet Kaur, Nir Stanietzky   +11 more
wiley   +1 more source

A review of artificial intelligence in brachytherapy

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Artificial intelligence (AI) has the potential to revolutionize brachytherapy's clinical workflow. This review comprehensively examines the application of AI, focusing on machine learning and deep learning, in various aspects of brachytherapy.
Jingchu Chen, Richard L. J. Qiu, Tonghe Wang, Shadab Momin, Xiaofeng Yang   +4 more
wiley   +1 more source

On cabled knots, Dehn surgery, and left-orderable fundamental groups [PDF]

arXiv, 2011
Previous work of the authors establishes a criterion on the fundamental group of a knot complement that determines when Dehn surgery on the knot will have a fundamental group that is not left-orderable. We provide a refinement of this criterion by introducing the notion of a decayed knot; it is shown that Dehn surgery on decayed knots produces surgery ...
arxiv