Results 51 to 60 of about 211,573 (276)

Blood loss in primary total knee arthroplasty-body temperature is not a significant risk factor-a prospective, consecutive, observational cohort study [PDF]

, 2015
BACKGROUND: Hypothermia related to anaesthesia and operating theatre environment is associated with increased blood loss in a number of surgical disciplines, including total hip arthroplasty.
Beller, Elaine, Dan, Michael, Jones, Peter, Liu, David, Martos, Sara Martinez, Randle, Ray   +5 more
core   +2 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Finite element model set-up of colorectal tissue for analyzing surgical scenarios [PDF]

, 2017
Finite Element Analysis (FEA) has gained an extensive application in the medical field, such as soft tissues simulations. In particular, colorectal simulations can be used to understand the interaction with the surrounding tissues, or with instruments ...
Bici, Michele, Bini, Fabiano, Campana, Francesca, Guachi, Robinson, Marinozzi, Franco   +4 more
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Landmark registration in CT for lung model approximation in EIT

Current Directions in Biomedical Engineering
For the visualization of pulmonary ventilation with Electrical Impedance Tomography (EIT), most devices rely on generalized reconstruction models. Yet, fixed thorax dimensions, predetermined electrode locations, and standard lung shapes lead to multiple ...
Fuchs Reinhard, Unger Michael, Wolfgang Reske Andreas, Neumuth Thomas   +3 more
doaj   +1 more source

Method for the Quantification of mHealth Related Physical Activity Intensity Using Consumer Mobile Sensors

Applied Sciences, 2023
Daily physical activity is one of the key factors to improve health and support the prevention of a variety of chronic diseases e.g., hypertension, depression or acute events such as strokes. Self-monitoring by the patients has shown to improve adherence
Jean-Baptiste Tylcz, Max Schreiber, Dominik Michalski, Joseph Classen, Galina Ivanova   +4 more
doaj   +1 more source

Computer-assisted radiographic calculation of spinal curvature in brachycephalic "screw-Tailed" dog breeds with congenital thoracic vertebral malformations: reliability and clinical evaluation [PDF]

, 2014
The objectives of this study were: To investigate computer-assisted digital radiographic measurement of Cobb angles in dogs with congenital thoracic vertebral malformations, to determine its intra- and inter-observer reliability and its association with ...
Faller, Kiterie, Guevar, Julien, Gutierrez Quintana, Rodrigo, Penderis, Jacques, Stalin, Catherine, Yeamans, Carmen   +5 more
core   +3 more sources

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

In Situ Visualization for 3D Ultrasound-Guided Interventions with Augmented Reality Headset

Bioengineering, 2021
Augmented Reality (AR) headsets have become the most ergonomic and efficient visualization devices to support complex manual tasks performed under direct vision.
Nadia Cattari, Sara Condino, Fabrizio Cutolo, Mauro Ferrari, Vincenzo Ferrari   +4 more
doaj   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source