Results 61 to 70 of about 455,686 (318)

Indications for Computer-Assisted Surgery in Otorhinolaryngology [PDF]

Computer Aided Surgery, 1998
Indications for the use of computer-assisted surgery (CAS) in otorhinolaryngology can be grouped into several domains including the following: difficult cases involving the anterior, middle, and posterior skull base, especially the rhinobasis or laterobasis, and diseases of the petrous bone, the infratemporal fossa, the retromaxillar space, and the ...
W, Mann, L, Klimek
openaire   +2 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Image stitching for real-time laparoscopic hyperspectral imaging

Scientific Reports
Hyperspectral imaging (HSI) shows significant promise in the medical field for tissue detection and perfusion assessment. To extend its application to intraoperative diagnosis, laparoscopic cameras combining a high resolution color video and simultaneous
Marie-Sophie von Braun, Annekatrin Pfahl, Andreas Melzer, Claire Chalopin, Hannes Köhler   +4 more
doaj   +1 more source

Guiding the surgical gesture using an electro-tactile stimulus array on the tongue: A feasibility study [PDF]

, 2007
Under conventional "open-" surgery, the physician has to take care of the patient, interact with other clinicians and check several monitoring devices. Nowadays, the Computer Assisted Surgery proposes to integrate 3D cameras in the operating theatre in ...
Boy, Frédéric, Demongeot, Jacques, Orliaguet, Jean-Pierre, Payan, Yohan, Robineau, Fabien   +4 more
core   +4 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Surgical workflow simulation for the design and assessment of operating room setups in orthopedic surgery

BMC Medical Informatics and Decision Making, 2020
Background The design and internal layout of modern operating rooms (OR) are influencing the surgical team’s collaboration and communication, ergonomics, as well as intraoperative hygiene substantially.
Juliane Neumann, Christine Angrick, Celina Höhn, Dirk Zajonz, Mohamed Ghanem, Andreas Roth, Thomas Neumuth   +6 more
doaj   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Comparison of Surface Area across the Allograft-Host Junction Site Using Conventional and Navigated Osteotomy Technique. [PDF]

, 2012
Bulk allograft reconstruction plays an important role in limb-salvage surgery; however, non-union has been reported in up to 27% of cases. The purpose of this study is to quantify average surface contact areas across simulated intraoperative osteotomies ...
Abraham, John A, Geller, David S, Gorlick, Richard G, Hohn, Eric, Kim, Mimi Y, Lall, Ajay   +5 more
core   +2 more sources

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Method for the Quantification of mHealth Related Physical Activity Intensity Using Consumer Mobile Sensors

Applied Sciences, 2023
Daily physical activity is one of the key factors to improve health and support the prevention of a variety of chronic diseases e.g., hypertension, depression or acute events such as strokes. Self-monitoring by the patients has shown to improve adherence
Jean-Baptiste Tylcz, Max Schreiber, Dominik Michalski, Joseph Classen, Galina Ivanova   +4 more
doaj   +1 more source