Results 21 to 30 of about 6,584,741 (301)

Does bariatric surgery prior to total hip or knee arthroplasty reduce post-operative complications and improve clinical outcomes for obese patients? Systematic review and meta-analysis. [PDF]

, 2016
AIMS: Our aim was to determine whether, based on the current literature, bariatric surgery prior to total hip (THA) or total knee arthroplasty (TKA) reduces the complication rates and improves the outcome following arthroplasty in obese patients. METHODS:
Aboelmagd, T, Hing, CB, MacGregor, A, Smith, TO   +3 more
core   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

Expert Consensus on Community Management of Diagnosis and Treatment of Osteoarthritis and Osteoporosis in the Elderly (Version 2023)

Xiehe Yixue Zazhi, 2023
The prevalence of osteoarthritis (OA) and osteoporosis (OP) in China is increasing every year and they are often co-affected, seriously affecting the health and quality of life of elderly people.
Joint Surgery Group of Beijing Medical Association Orthopaedic Branch
doaj   +1 more source

Fifty Years of Innovation in Plastic Surgery [PDF]

, 2016
© 2016 The Korean Society of Plastic and Reconstructive Surgeons.Background Innovation has molded the current landscape of plastic surgery. However, documentation of this process only exists scattered throughout the literature as individual articles. The
Darzi, A, Hettiaratchy, S, Hughes-Hallett, Kwasnicki, Marcus, HJ, Yang, GZ   +5 more
core   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Christian Albert Theodor Billroth, M.D., founding father of abdominal surgery (1829-1894). [PDF]

, 2012
In the 1800s, the field of surgery was in its infancy, somewhat primitive and embryonic. The technical nature of surgery was the basis for the dividing line between the disciplines of surgery and internal medicine. Sterilization was not a common practice.
Cowan, MD, Scott W., Fong, B.S., Zhi Ven, Lavu, MD, Harish, Rosato, MD, Ernest L., Yeo, MD, Charles J.   +4 more
core   +1 more source

Laparoscopic versus open colorectal resection for cancer and polyps: A cost-effectiveness study [PDF]

, 2014
Methods: Participants were recruited in 2006-2007 in a district general hospital in the south of England; those with a diagnosis of cancer or polyps were included in the analysis.
Dowson, H, Gage, H, Jackson, D, Jordan, J, Rockall, T   +4 more
core   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

Day surgery and general anaesthesia : what makes patients anxious? [PDF]

, 2010
For many patients the prospective of undergoing surgery and general anaesthesia is highly anxiety provoking. With the global rise in day surgery and limited nurse/ patient contact, anxiety has become a prominent issue.
Mitchell, MJ
core   +1 more source

Fellowship training in Acute Care Surgery: from inception to current state. [PDF]

, 2016
Recognizing the need for urgent and emergent surgical care across America, the American Association for the Surgery of Trauma developed and implemented, and oversees, the Acute Care Surgery Fellowship Training Program.
Davis, Kimberly, Jurkovich, Gregory
core   +1 more source