Results 31 to 40 of about 6,584,741 (301)

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

Potential Predictors that Influence Women to Undergo Cosmetic Surgery [PDF]

, 2017
There may be relationships among collectivism, self-esteem, and religiousness in relation to individual acceptance of cosmetic surgery. This present study hypothesized that both self-esteem and religiousness would be negatively correlated with individual
Han, Eun Jin
core   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

Acute mesenteric ischemia: updated guidelines of the World Society of Emergency Surgery [PDF]

, 2022
Miklosh Bala, Fausto Catena, Jeffry L. Kashuk, Belinda De Simone, Carlos Augusto Gomes, Dieter Weber, Massimo Sartelli, Federico Coccolini, Yoram Kluger, Fikri M. Abu‐Zidan, Edoardo Picetti, Luca Ansaloni, Goran Augustin, Walter L. Biffl, Marco Ceresoli, Osvaldo Chiara, Massimo Chiarugi, Raúl Coimbra, Yunfeng Cui, Dimitrios Damaskos, Salomone Di Saverio, Joseph M. Galante, Vladimir Khokha, Andrew W. Kirkpatrick, Kenji Inaba, Ari Leppäniemi, Andrey Litvin, Andrew B. Peitzman, Vishal G. Shelat, Michael Sugrue, Matti Tolonen, Sandro Rizoli, Ibrahima Sall, Solomon Gurmu Beka, Isidoro Di Carlo, Richard P. G. ten Broek, Chirika Mircea, Giovanni Domenico Tebala, Michele Pisano, Harry van Goor, Ronald V. Maier, Hans Jeekel, Ian Civil, Andreas Hecker, Edward Tan, Kjetil Søreide, Matthew J. Lee, Imtiaz Wani, Luigi Bonavina, Mark A. Malangoni, Kaoru Koike, George C. Velmahos, Gustavo Pereira Fraga, Andreas Fette, Nicola de’Angelis, Zsolt J. Balogh, Thomas M. Scalea, Gabriele Sganga, Michael D. Kelly, Jim Khan, Philip F. Stahel, Ernest E. Moore   +61 more
openalex   +1 more source

Orthogeriatric Multidisciplinary Co-Management Across Acute and Rehabilitation Care Improves Length of Stay, Functional Outcomes and Complications in Geriatric Hip Fracture Patients

Geriatric Orthopaedic Surgery & Rehabilitation, 2022
Introduction As the global number of geriatric hip fracture cases continues to proliferate, a newly developed orthogeriatric co-management multidisciplinary care model has been implemented since November 2018 to meet further increases in demand.
Dennis King Hang Yee MBBS(HK), FRCSEd, FHKCOS, FHKAM(Orthopaedic Surgery), Tak-Wing Lau MBBS(HK), FRCSEd, FHKCOS, FHKAM(Orthopaedic Surgery), Christian Fang MBBS(HK), FRCSEd, FHKCOS, FHKAM(Orthopaedic Surgery), Kathine Ching BSc (Hons), Jake Cheung MChem (Hons), Frankie Leung MBBS(HK), FRCSEd, FHKCOS, FHKAM(Orthopaedic Surgery)   +5 more
doaj   +1 more source

Immediate Reconstruction of the Nipple-areola Complex Using Inferior Pedicle Skin for Central Tumors of the Breast

Plastic and Reconstructive Surgery, Global Open, 2022
Summary:. The nipple-areola complex (NAC) must be considered as an integral part of the breast with regard to morale and self-assurance. Achieving good aesthetic outcome is a challenge after excision of the NAC in retroareolar tumors.
John Mathew, MS, DM, FRCS (Edin), FRCS (G Surgery)
doaj   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

Critical care provision after colorectal cancer surgery [PDF]

, 2016
Background: Colorectal cancer (CRC) is the 2nd largest cause of cancer related mortality in the UK with 40 000 new patients being diagnosed each year. Complications of CRC surgery can occur in the perioperative period that leads to the requirement of ...
Dale, C.D., Kinsella, J., McLoone, P., Morrison, D., Puxty, K., Quasim, T., Sloan, B.   +6 more
core   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

PREVALENSI KEJADIAN PONV PADA PEMBERIAN MORFIN SEBAGAI ANALGETIK PASCA OPERASI PENDERITA TUMOR PAYUDARA DENGAN ANESTESI UMUM DI RSUP DR. KARIADI SEMARANG [PDF]

, 2015
Background Morphine is the most abundant analgesic which commonly used for post mastectomy’s pain reliever. Altough, it is potentially cause the adverse effect such as nausea and vomiting.
Dwi Jatmiko, Heru, Qudsi, Alfiani Sofia
core