Results 31 to 40 of about 6,669,709 (347)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Contact surgery and supporting open books

open access: yes, 2012
Let $(M,\xi)$ be a contact 3-manifold. We present two new algorithms, the first of which converts an open book $(\Sigma,\Phi)$ supporting $(M,\xi)$ with connected binding into a contact surgery diagram. The second turns a contact surgery diagram for $(M,\
Avdek, Russell
core   +1 more source

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

open access: yesFEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello   +6 more
wiley   +1 more source

Christian Albert Theodor Billroth, M.D., founding father of abdominal surgery (1829-1894). [PDF]

open access: yes, 2012
In the 1800s, the field of surgery was in its infancy, somewhat primitive and embryonic. The technical nature of surgery was the basis for the dividing line between the disciplines of surgery and internal medicine. Sterilization was not a common practice.
Cowan, MD, Scott W.   +4 more
core   +1 more source

Trends of intervention for paediatric stone disease over the last two decades (2000–2015): A systematic review of literature [PDF]

open access: yes, 2017
Objective: To ascertain the publication trends of interventions for paediatric kidney stone disease (KSD) we conducted a systematic review of literature over the last 16 years.
Aboumarzouk, Omar   +6 more
core   +2 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Orthogeriatric Multidisciplinary Co-Management Across Acute and Rehabilitation Care Improves Length of Stay, Functional Outcomes and Complications in Geriatric Hip Fracture Patients

open access: yesGeriatric Orthopaedic Surgery & Rehabilitation, 2022
Introduction As the global number of geriatric hip fracture cases continues to proliferate, a newly developed orthogeriatric co-management multidisciplinary care model has been implemented since November 2018 to meet further increases in demand.
Dennis King Hang Yee MBBS(HK), FRCSEd, FHKCOS, FHKAM(Orthopaedic Surgery)   +5 more
doaj   +1 more source

Immediate Reconstruction of the Nipple-areola Complex Using Inferior Pedicle Skin for Central Tumors of the Breast

open access: yesPlastic and Reconstructive Surgery, Global Open, 2022
Summary:. The nipple-areola complex (NAC) must be considered as an integral part of the breast with regard to morale and self-assurance. Achieving good aesthetic outcome is a challenge after excision of the NAC in retroareolar tumors.
John Mathew, MS, DM, FRCS (Edin), FRCS (G Surgery)
doaj   +1 more source

Iatrogenic Spinal Cord Injury Resulting From Cervical Spine Surgery. [PDF]

open access: yes, 2017
STUDY DESIGN: Retrospective cohort study of prospectively collected data. OBJECTIVE: To examine the incidence of iatrogenic spinal cord injury following elective cervical spine surgery.
Arnold, Paul M.   +15 more
core   +2 more sources

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