Results 51 to 60 of about 3,346,470 (263)

Barriers and Enablers of Electronic Health Literacy in Colorectal Cancer Patients: A Phenomenological Study

Patient Preference and Adherence
Yanhua Xu,1 Qun Chen,1 Min Wang,2 Yichen Lu3 1Gastrointestinal Surgery Department, The Affiliated Taizhou People’s Hospital of Nanjing Medical University, Taizhou, Jiangsu Province, People’s Republic of China; 2Surgical Department, The Affiliated Taizhou
Xu Y, Chen Q, Wang M, Lu Y
doaj  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Assessment of Hand Hygiene Knowledge, Attitude, and Practice Among Health Sciences Students in Herat, Afghanistan: A Cross-Sectional Study

Risk Management and Healthcare Policy
Enayatollah Ejaz,1 Mohammad Masudi,1,2 Ali Rahimi,1– 3 Khadejah Osmani,4 Nasar Ahmad Shayan5 1Department of Curative Medicine, Faculty of Medicine, Jami University, Herat, Afghanistan; 2Department of Pediatrics, Faculty of Medicine, Herat University ...
Ejaz E, Masudi M, Rahimi A, Osmani K, Shayan NA   +4 more
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CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Prognostic Value of Ki-67 and Progesterone Receptor for Risk Stratification and Outcomes by Adjuvant Chemotherapy in Early Luminal-Type Breast Cancer

Breast Cancer: Targets and Therapy
Hung-Hsun Chen,1,* Shu-Jyuan Chang,2,* Jung-Yu Kan,1 Fang-Ming Chen,1,3 Chung-Liang Li,1,3 Hidenobu Takahashi,1,3 Shen-Liang Shih,1,3 Ming-Feng Hou,1,3,4 Mei-Ren Pan,2,4 Ping-Fu Yang,1,3,* Chi-Wen Luo1,5 1Division of Breast ...
Chen HH, Chang SJ, Kan JY, Chen FM, Li CL, Takahashi H, Shih SL, Hou MF, Pan MR, Yang PF, Luo CW   +10 more
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CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

The Application of Retrograde Intrarenal Surgery to Remove a Single Large Kidney Stone During Pregnancy [Corrigendum]

Research and Reports in Urology
Jongjitaree K, Taweemonkongsap T, Leewansangtong S, Srinualnad S, Chotikawanich E. Res Rep Urol. 2020;12:351–355. Page 354, Ethical Approval section, the text “The publication of this study was approved by the Ethics Committee of ...
Jongjitaree K, Taweemonkongsap T, Leewansangtong S, Srinualnad S, Chotikawanich E   +4 more
doaj  

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Aneurysmal Veins in Free Flaps: A Rare Case Report and Discussion

Plastic and Reconstructive Surgery, Global Open
Summary:. Microvascular anastomosis is a fundamental technique in reconstructive surgery, where careful selection and meticulous handling of vessels are critical in preventing thrombosis—the leading cause of flap failure. Despite the extensive literature
Manisha Anbudurai, MBBS, Louis Choon Kit Wong, MD, Christelle Guillon, MBBS, MRCS (Eng), Yishan Valerie Tuang, MBBS, Priya Tiwari, MMed (Surg), FAMS (Plastic Surgery), Yan Lin Yap, MMed (Surg), FAMS (Plastic Surgery), Thiam Chye Lim, FRCS (Edin), AM (Mal), FAMS (Plastic Surgery), Jane Lim, FRCS (Edin), FRCS (Glasg), FAMS (Plastic Surgery), Vigneswaran Nallathamby, MMed (Surg), FAMS (Plastic Surgery), O-Wern Low, FRCS (Plast) (Glasg), FAMS (Plastic Surgery)   +9 more
doaj   +1 more source