Results 71 to 80 of about 6,007,559 (305)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Iatrogenic Spinal Cord Injury Resulting From Cervical Spine Surgery. [PDF]
, 2017 STUDY DESIGN: Retrospective cohort study of prospectively collected data. OBJECTIVE: To examine the incidence of iatrogenic spinal cord injury following elective cervical spine surgery.
Arnold, Paul M. +15 more
core +2 more sources
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Exploration and Validation of Key Genes and Immune Infiltration in Alcoholic Hepatitis
Journal of Inflammation ResearchYingna Mei,1 Yitao Zheng,2 Xingfen Zhang,1 Ting Hu,1 Xiaoqing Zheng,1 Cui Zhang,3 Qinzhi Deng1 1Department of Liver Disease, Ningbo No.2 Hospital, Ningbo, People’s Republic of China; 2Department of Pancreatic and Gastrointestinal Surgery Division, Ningbo
Mei Y +6 more
doaj
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Risk Management and Healthcare PolicyMohammad Masudi,1,2 Ali Rahimi,1,2 Enayatollah Ejaz,1,2 Khadejah Osmani,3 Nasar Ahmad Shayan4 1Department of Curative Medicine, Faculty of Medicine, Jami University, Herat, Afghanistan; 2Department of Pediatrics, Faculty of Medicine, Herat University ...
Masudi M +4 more
doaj
Perturbative 3-manifold invariants by cut-and-paste topology
, 1999 We give a purely topological definition of the perturbative quantum invariants of links and 3-manifolds associated with Chern-Simons field theory. Our definition is as close as possible to one given by Kontsevich.
Kuperberg, Greg, Thurston, Dylan P.
core
PREVALENSI KEJADIAN PONV PADA PEMBERIAN MORFIN SEBAGAI ANALGETIK PASCA OPERASI PENDERITA TUMOR PAYUDARA DENGAN ANESTESI UMUM DI RSUP DR. KARIADI SEMARANG [PDF]
, 2015 Background Morphine is the most abundant analgesic which commonly used for post mastectomy’s pain reliever. Altough, it is potentially cause the adverse effect such as nausea and vomiting.
Dwi Jatmiko, Heru, Qudsi, Alfiani Sofia
core
Estimating the risk of adverse birth outcomes in pregnant women undergoing non-obstetric surgery using routinely collected NHS data: an observational study [PDF]
, 2016 Background: Previous research suggests that non-obstetric surgery is carried out in 1 – 2% of all pregnancies. However, there is limited evidence quantifying the associated risks.
Aylin, P +6 more
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source