Results 71 to 80 of about 3,346,470 (263)
From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care
Molecular Oncology, EarlyView.Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard +8 more
wiley +1 more source
Pediatric Burns at The Rift Valley Provincial General Hospital, Nakuru, Kenya
The Annals of African Surgery, 2010 Aim: To determine the etiology and outcome of pediatric burns (0-12 years). Design: A retrospective study of burn victims hospitalized at the Rift Valley Provincial General Hospital, Nakuru, Kenya from April 2004 to March 2007 Method: Charts of all
Oduor P.R., MBChB, MMed, Department of Surgery
doaj
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Ten-year follow-up of direct interposition graft repair of persistent sciatic artery aneurysm
Journal of Vascular Surgery Cases and Innovative Techniques, 2021 Sunil Rajendran, MS, DNB, MRCSEd, ChM Vascular Surgery +2 more
doaj +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
Patellar Reconstruction During Total Knee Arthroplasty for Previous Patellectomy
Arthroplasty TodayPatellectomy, an uncommon procedure in the current era, poses a challenge in total knee arthroplasty (TKA), creating anteroposterior instability, anterior knee pain, and loss of mechanical advantage. The TKA is even more complicated when the patellectomy
Chun Man Lawrence Lau, MBChB, MRCSEd, FRCSEd (Orth), FHKCOS, FHKAM (Orthopaedic Surgery), PhD +6 more
doaj +1 more source
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Plastic and Reconstructive Surgery, Global OpenSummary:. Liposuction has become a highly common procedure performed by plastic surgeons since its advent in 1979. However, it is not without risk. The authors report their experience with breakage and retention of the tip of a liposuction infiltration ...
Christelle Guillon, MBBS, MRCS (Eng) +2 more
doaj +1 more source