Results 71 to 80 of about 5,943,631 (302)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Barriers and Enablers of Electronic Health Literacy in Colorectal Cancer Patients: A Phenomenological Study

open access: yesPatient Preference and Adherence
Yanhua Xu,1 Qun Chen,1 Min Wang,2 Yichen Lu3 1Gastrointestinal Surgery Department, The Affiliated Taizhou People’s Hospital of Nanjing Medical University, Taizhou, Jiangsu Province, People’s Republic of China; 2Surgical Department, The Affiliated Taizhou
Xu Y, Chen Q, Wang M, Lu Y
doaj  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Assessment of Hand Hygiene Knowledge, Attitude, and Practice Among Health Sciences Students in Herat, Afghanistan: A Cross-Sectional Study

open access: yesRisk Management and Healthcare Policy
Enayatollah Ejaz,1 Mohammad Masudi,1,2 Ali Rahimi,1– 3 Khadejah Osmani,4 Nasar Ahmad Shayan5 1Department of Curative Medicine, Faculty of Medicine, Jami University, Herat, Afghanistan; 2Department of Pediatrics, Faculty of Medicine, Herat University ...
Ejaz E   +4 more
doaj  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

The Application of Retrograde Intrarenal Surgery to Remove a Single Large Kidney Stone During Pregnancy [Corrigendum]

open access: yesResearch and Reports in Urology
Jongjitaree K, Taweemonkongsap T, Leewansangtong S, Srinualnad S, Chotikawanich E. Res Rep Urol. 2020;12:351–355. Page 354, Ethical Approval section, the text “The publication of this study was approved by the Ethics Committee of ...
Jongjitaree K   +4 more
doaj  

Orthopaedic surgery [PDF]

open access: yes, 2005
Over the past fifty years orthopaedic surgery made giant strides forward. It developed from a discipline that dealt primarily with the treatment of fractures, bone infections and tendon transfers and that treated degenerate joints by fusing them to one ...
Grixti, Charles J.
core  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Prognostic Value of Ki-67 and Progesterone Receptor for Risk Stratification and Outcomes by Adjuvant Chemotherapy in Early Luminal-Type Breast Cancer

open access: yesBreast Cancer: Targets and Therapy
Hung-Hsun Chen,1,* Shu-Jyuan Chang,2,* Jung-Yu Kan,1 Fang-Ming Chen,1,3 Chung-Liang Li,1,3 Hidenobu Takahashi,1,3 Shen-Liang Shih,1,3 Ming-Feng Hou,1,3,4 Mei-Ren Pan,2,4 Ping-Fu Yang,1,3,* Chi-Wen Luo1,5 1Division of Breast ...
Chen HH   +10 more
doaj  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

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