Results 71 to 80 of about 72,904 (298)

Presence Of A Congenitally Bicuspid Aortic Valve Among Patients Having Combined Mitral And Aortic Valve Replacement [PDF]

, 2012
Although bicuspid aortic valve occurs in an estimated 1% of adults and mitral valve prolapse in an estimated 5% of adults, occurrence of the 2 in the same patient is infrequent.
Hamman, Baron Lloyd, Hebeler, Robert Frederick, Janning, Kaitlin Georgeanne, Ko, Jong Mi, Roberts, William Clifford, Vowels, Travis James   +5 more
core   +1 more source

Trends in Isolated Surgical Aortic Valve Replacement

JACC: Cardiovascular Interventions, 2019
We read with interest the paper by Kundi et al. [(1)][1] that assessed trends in transcatheter aortic valve replacement (TAVR) and surgical aortic valve replacement (SAVR) volume, and the effect of TAVR volume on SAVR mortality.
Paula D, Strassle, Sameer, Arora, John P, Vavalle   +2 more
openaire   +2 more sources

Amyloid β Instigates Cardiac Neurotrophic Signaling Impairment, Driving Alzheimer's Associated Heart Disease

Advanced Science, EarlyView.
This research identified cardiac amyloid pathology, neurotrophic factor depletion, and reduced myocardial nerve function in a transgenic model of cerebral amyloidosis (Tg2576), Aβ‐challenged cardiomyocytes, and in human AD heart tissue. These findings carry significant diagnostic and therapeutic implications, emphasizing the role of neuro‐signaling ...
Andrea Elia, Rebecca Parodi‐Rullan, Rafael Vazquez‐Torres, Ashley Carey, Huaqing Zhao, Sabzali Javadov, Silvia Fossati   +6 more
wiley   +1 more source

Totally endoscopic aortic valve replacement with concomitant trans-aortic mitral valve repair for mitral regurgitation

Journal of Cardiothoracic Surgery, 2021
Background Minimally invasive aortic valve procedures through a hemi-sternotomy or a right anterior mini-thoracotomy have gained popularity over the last several years.
Antonios Pitsis, Nikolaos Tsotsolis, Harisios Boudoulas, Konstantinos Dean Boudoulas   +3 more
doaj   +1 more source

Cardiac interventions in patients with achondroplasia: a systematic review. [PDF]

, 2020
Patients with achondroplasia and other causes of dwarfism suffer from increased rates of cardiovascular disease relative to the remainder of the population.
Choi, Jae Hwan, Gordon, Jonathan S, Maynes, Elizabeth J, O\u27Malley, Thomas J, Phan, Kevin, Sukhavasi, Amrita, Tchantchaleishvili, Vakhtang   +6 more
core   +1 more source

Patient-specific image-based computer simulation for theprediction of valve morphology and calcium displacement after TAVI with the Medtronic CoreValve and the Edwards SAPIEN valve [PDF]

, 2016
AIMS: Our aim was to validate patient-specific software integrating baseline anatomy and biomechanical properties of both the aortic root and valve for the prediction of valve morphology and aortic leaflet calcium displacement after TAVI.
Bosmans, B, Bosmans, J, Bruining, N, Chevalier, B, Collas, V, De Beule, Mathieu, de Jaegere, P, De Santis, Gianluca, Dezutter, Tim, El Faquir, N, Lefèvre, T, Mortier, Peter, Rahhab, Z, Rodriguez-Olivares, R, Schultz, C, Segers, Patrick, van Mieghem, N, Verhegghe, Benedict, Watanabe, Y   +18 more
core   +1 more source

A Soft Robotic Model for Simulating Heart Valve Disease and Cardiac Interventions

Advanced Science, EarlyView.
This paper introduces a fully synthetic fabrication methodology for a soft robotic, in‐vitro model of the left‐heart, complete with a functioning mitral valve apparatus. With a view towards patient‐specific modeling, we demonstrate physiological flow and pressure waveforms, tunable mitral valve function with clinical imaging compatibility, and its use ...
James Davies, Emanuele Nicotra, Kefan Zhu, Chi Cong Nguyen, Bibhu Sharma, Adrienne Ji, Phuoc Thien Phan, Jingjing Wan, Patrick Pruscino, Hermione Truong, Jelena Rnjak‐Kovacina, Hoang‐Phuong Phan, Christopher Hayward, Nigel Hamilton Lovell, Thanh Nho Do   +14 more
wiley   +1 more source

Transcatheter aortic valve implantation with SAPIEN 3 versus surgical aortic valve replacement in patients with symptomatic severe aortic stenosis at low risk of surgical mortality: a cost-utility analysis for Switzerland

Swiss Medical Weekly
AIMS OF THE STUDY: The 2021 European Society of Cardiology Guidelines on valvular heart disease recommend transcatheter aortic valve implantation (TAVI) for patients with symptomatic severe aortic stenosis at low surgical risk and age ≥75 years who are ...
Christophe Alain Wyss, Roberto Corti, Thomas Nestelberger, Pascal Candolfi, Alexis Delbaere, Barbara Fischer, Matthias Schwenkglenks, Harry Telser   +7 more
doaj   +1 more source

F‐Box and Leucine‐Rich Repeat Protein 4 (FBXL4) Maintains Sarcomere Integrity and Cardiac Function by Enhancing K48‐Linked Ubiquitinated Degradation of Profilin‐1 (PFN1)

Advanced Science, EarlyView.
Schematic diagram depicting the proposed signaling mechanisms underlying the effects of FBXL4 in the setting of cardiac hypertrophy. Under hypertrophic stimulation, cardiomyocytes‐specific overexpression FBXL4 maintains sarcomere integrity and cardiac function by enhancing K48‐linked ubiquitinated degradation of PFN1 at the K70 site.
Xingda Li, Xueqi He, Xinyuan Hao, Yu Zhang, Xin Zhao, Shuang Wang, Zhenru Wang, Haonan Du, Hongda Li, Lian Yi, Zhimin Du, Weijie Du   +11 more
wiley   +1 more source

Transcatheter Aortic Valve Durability: Focus on Structural Valve Deterioration

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Transcatheter aortic valve replacement has emerged as a valuable alternative to surgical aortic valve replacement in patients with severe aortic stenosis. Given the expansion of transcatheter aortic valve replacement to lower‐risk and younger populations
Antonin Trimaille, Adrien Carmona, Sandy Hmadeh, Dinh Phi Truong, Benjamin Marchandot, Shinnosuke Kikuchi, Kensuke Matsushita, Patrick Ohlmann, Valérie Schini‐Kerth, Josep Rodés‐Cabau, Philippe Pibarot, Olivier Morel   +11 more
doaj   +1 more source