Results 181 to 190 of about 1,019,528 (265)

Sarcopenia Is Associated With Severe Treatment Toxicity and Mortality in Older Adults With Advanced Cancer: A Secondary Analysis

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 5, October 2026.
ABSTRACT Background Sarcopenia, a loss of muscle strength, quantity and performance that occurs primarily from ageing or secondary to disease, is hypothesized to worsen treatment outcomes in patients with cancer. Most published studies, however, focus solely on muscle quantity in patients under 70.
Lindsey J. Mattick, Mostafa Mohammed, Chin‐Shang Li, Rachael G. Tylock, Kah Poh Loh, Marie A. Flannery, Luke J. Peppone, Po‐Ju Lin, Marcus D. Goncalves, Bette J. Caan, Elizabeth M. Cespedes Feliciano, Karteek Popuri, Mirza Faisal Beg, James D. Bearden, Jeffrey Berenberg, Khalil Katato, Karen M. Mustian, Supriya G. Mohile, Richard F. Dunne   +18 more
wiley   +1 more source

Conserved and Tissue‐Specific RNA and Protein Cargos of Small Extracellular Vesicles From 120 Tissue Sites Across 34 Organs in a Single Pig

Journal of Extracellular Vesicles, Volume 15, Issue 10, October 2026.
A whole‐body map of sEVs from a single pig, including 133 samples spanning 10 systems, revealed striking tissue‐specific heterogeneity in yield. Importantly, a conserved core cargo set comprising candidate sEV markers (ACTG1, CFL1, and ANXA2), RNA‐binding proteins, the let‐7 miRNA family, and ferritin genes was defined from 105,409 (88.6% full‐length ...
Naixiang Yu, Jinxiu Liu, Chenliang Lai, Siyi Liu, Jiacheng Wei, Jiahong Zhong, Sanya Xiong, Qingjie Zeng, Junwu Ma, Zhou Zhang, Zhiyan Zhang   +10 more
wiley   +1 more source

Use of Meloxicam or Ketoprofen for Piglet Pain Control Following Surgical Castration. [PDF]

Front Vet Sci, 2018
Viscardi AV, Turner PV.
europepmc   +1 more source

Ablative radiotherapy in castration‐resistant prostate cancer

BJU International, Volume 138, Issue 4, Page 659-665, October 2026.
Objective To prove the oncological benefit of ablative radiotherapy in patients with up to five metastases from castration‐resistant prostate cancer (CRPC) a single‐centre randomised trial was initiated. Patients and Methods This monocentric, randomised, phase II clinical trial enrolled patients with up to five prostate‐specific membrane antigen ...
Tobias Hölscher, Fabian Lohaus, Lydia Koi, Jörg Kotzerke, Sebastian Hoberück, Christian Thomas, Angelika Borkowetz, Steffen Löck, Mechthild Krause, Esther G.C. Troost   +9 more
wiley   +1 more source

The age of surgical castration affects the healing process in beef calves. [PDF]

Transl Anim Sci, 2017
Norring M, Mintline EM, Tucker CB.
europepmc   +1 more source

Acute anaphylactic and multiorgan inflammatory effects of Comirnaty in pigs: evidence of spike protein mRNA transfection and paralleling inflammatory cytokine upregulation

British Journal of Pharmacology, Volume 183, Issue 20, Page 6225-6239, October 2026.
Abstract Background and Purpose Rare but severe adverse events (AEs) associated with mRNA‐lipid nanoparticle (LNP) COVID‐19 vaccines, such as Comirnaty, include anaphylaxis and inflammatory organ disorders, but their underlying mechanisms are poorly understood. We aimed to develop an animal model to study these phenomena.
László Dézsi, Gábor Kökény, Gábor Szénási, Csaba Révész, Tamás Mészáros, Bálint A. Barta, Réka Facsko, Anna Szilasi, Tamás Bakos, Gergely T. Kozma, Attila B. Dobos, Béla Merkely, Tamás Radovits, János Szebeni   +13 more
wiley   +1 more source

The role of macrophage migration inhibitory factor (MIF) in the pathogenesis and progression of cardiovascular disease

British Journal of Pharmacology, Volume 183, Issue 19, Page 5732-5751, October 2026.
Abstract Cardiovascular disease (CVD) remains the leading global cause of death, driven by complex mechanisms, in which chronic inflammation plays a central role. Inflammatory pathways contribute to all stages of CVD, from endothelial dysfunction and plaque formation to erosion, rupture and myocardial injury.
Shreya Mahabhashyam, James Harris, Jürgen Bernhagen, Antony Vinh, Katrina M. Mirabito Colafella   +4 more
wiley   +1 more source

Early‐stage crystalluria‐associated cystitis in a horse: Diagnostic value of serial urine sediment examination

Equine Veterinary Education, Volume 38, Issue 10, Page e690-e697, October 2026.
Summary Calcium carbonate crystals are commonly observed in equine urine; however, crystalluria without urolith formation rarely results in clinically significant disease. A 4‐year‐old Japanese Sport Horse developed recurrent haematuria accompanied by the presence of numerous angular calcium carbonate crystals. Discontinuing the calcium supplementation
R. Sato, S. Imai, A. Yamazaki, T. Miyazaki   +3 more
wiley   +1 more source

Divergent effects of hyperandrogenemia on the female reproductive neuroendocrine axis under different physiological conditions

Journal of Neuroendocrinology, Volume 38, Issue 10, October 2026.
Abstract The hypothalamic–pituitary–gonadal (HPG) axis coordinates reproductive function and incorporates gonadal sex steroid feedback to regulate gonadotropin secretion in a homeostatic manner. In females, ovarian estrogens and progestins act as the primary negative feedback signals to suppress luteinizing hormone (LH) release, whereas in males ...
Lillian Rose, Alexander S. Kauffman
wiley   +1 more source

Dermatological Adverse Events Associated With Lapatinib Treatment in Dogs With Urothelial Carcinoma: A Retrospective Study

Veterinary Dermatology, Volume 37, Issue 5, Page 752-760, October 2026.
Lapatinib is widely used in human oncology; however, dermatological adverse events (DAEs) are common and have been correlated with treatment efficacy. In veterinary medicine, lapatinib use in combination with piroxicam has been shown to be effective in treating canine urothelial carcinoma (UC); however, the incidence and prognostic significance of DAEs
Kosuke Horita, Tomohiro Yonezawa, Yasuyuki Momoi, Shingo Maeda   +3 more
wiley   +1 more source