Results 81 to 90 of about 1,019,468 (263)

Effect of age and castration method on neurohormonal, and electroencephalographic stress indicators in Holstein calves [PDF]

Master of ScienceDepartment of Clinical SciencesLuciana BergamascoAs public concern for food animal welfare increases, the need for objective pain assessment and methods to alleviate pain associated with production practices such as castration gains ...
Dockweiler, Jenna Corinne
core  

FAM107A loss facilitates TTK‐OPTN‐mediated mitophagy to drive docetaxel resistance in castration‐resistant prostate cancer

Interdisciplinary Medicine, EarlyView.
In the progression of docetaxel resistance, downregulation of FAM107A releases its transcriptional repression of TTK, leading to TTK upregulation. TTK enhances the interaction and phosphorylation of OPTN. This activates mitophagy in tumor cells, facilitates clearance of damaged mitochondria, reduces intracellular reactive oxygen species accumulation ...
Yishan Zhang, Fan Zou, Mingdong Wang, Chenyue Wu, Yingwei Xie, Yongjun Quan, Wei Yan, Yupeng Zheng, Lianhua Li, Yuexin Liu, Jian Yu, Hao Ping   +11 more
wiley   +1 more source

Transcriptomic profiling reveals differential muscle development and metabolic regulation in male Xizang sheep subjected to surgical vs. GnRH-immunocastration

Italian Journal of Animal Science
Castration is a common treatment modality for livestock and poultry; however, the conventional surgical method not only compromises animal welfare but also significantly impacts the economic viability of farming operations.
Tianzeng Song, Xiaoming Zhang, Gaofu Wang, Guiqiong Liu, Shehr Bano Mustafa, Khuram Shahzad, Xiaoying Chen, Ming Zhang, Xianyin Zeng, Mengjun Liu, Jianzhao Cui, Wangsheng Zhao, Xunping Jiang   +12 more
doaj   +1 more source

Surgical Castration of Piglets – Challenges and Alternatives – A Review

Annals of Animal Science
Abstract The European Declaration on Alternatives to Surgical Castration of Pigs stipulated that from 2012, surgical castration could only be performed using anesthetics and/or analgesics, and that it would be completely abandoned by 2018. Many Member States disagreed with the conditions set out in the Declaration.
Anna Zalewska, Martyna Batorska, Justyna Więcek, Anna Rekiel, Marcin Sońta   +4 more
openaire   +2 more sources

Analysis of Notch1 and Notch3 Signaling Pathway Components in Benign Prostatic Hyperplasia and Prostate Cancer Patients

Journal of Clinical Laboratory Analysis, EarlyView.
This study evaluates the association between Notch1 and Notch3 genetic variations and serum protein levels in patients with benign prostatic hyperplasia and prostate cancer. While genetic variations showed no significant link to disease risk, serum protein levels were significantly lower in prostate cancer and metastatic groups compared to healthy ...
Emine Yagci, Cansu Ozbayer, Ata Ozen, Gamze Zengin, Hulyam Kurt   +4 more
wiley   +1 more source

Self-Administration of Meloxicam via Medicated Molasses Lick Blocks May Improve Welfare of Castrated Calves

Animals
The self-administration of meloxicam via medicated feed is a novel concept that could enable non-invasive, pre-emptive and long-term analgesia. Forty Bos taurus male calves were randomly allocated to four treatment groups: no castration (PC), surgical ...
Samantha Rudd, Sabrina Lomax, Peter J. White, Dominique Van der Saag   +3 more
doaj   +1 more source

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

Effects of neonatal surgical castration and immunocastration in male pigs on blood T lymphocytes and health markers

Animal, 2014
Surgical castration in pig husbandry is criticized for welfare reasons. Thus, it is necessary to evaluate alternative ways of rearing male pigs, such as entire or immunocastrated animals.
C. Leclercq, A. Prunier, E. Merlot
doaj   +1 more source

Primary BPH Stromal Cell Cultures Exhibit Heightened Androgen‐Responsiveness

The Prostate, EarlyView.
ABSTRACT Background Benign prostatic hyperplasia (BPH) is the most common disease in aging males. BPH growth is androgen‐dependent, and it appears that androgens preferentially stimulate the growth of BPH as compared to normal prostate. The mechanism of preferential androgen stimulation of BPH growth is not clear.
Wei Chen, Fulu Dong, Mohammad Reza Askarpour, Laura E. Pascal, Rajiv Dhir, Uma Chandran, Bruce L. Jacobs, Donald B. DeFranco, Naoki Yoshimura, Zhou Wang   +9 more
wiley   +1 more source

Evaluation of the effect of surgical and immunological castration of male pigs on boar taint compounds in oral fluid and fat tissue by LC-MS/MS method

Journal of Veterinary Research, 2020
An effective way of preventing undesirable boar taint in pork meat caused by the presence of androstenone, skatole and indole is surgical castration of piglets. This, however, arouses growing social opposition.
Woźniak Barbara, Cybulski Piotr, Jabłoński Artur, Witek Sebastian, Matraszek-Żuchowska Iwona   +4 more
doaj   +1 more source