Results 161 to 170 of about 34,275 (269)
ABSTRACT Background Methyl Methanesulfonate‐Sensitivity Protein 22‐Like (MMS22L) plays a key role in homology‐directed DNA repair, and experimental models have shown that its loss confers sensitivity to Poly (ADP‐ribose) polymerase inhibitors (PARPi).
Mayuko Kanayama +12 more
wiley +1 more source
Cytological and Pathological Characterization of Canine Neoplasm in and Around Bishoftu, Ethiopia
This study characterizes dog tumours cytologically and histopathologically in and around Bishoftu town. Mammary gland adenocarcinoma, papillary mammary adenocarcinoma, carcinoma–mixed type, Sertoli cell tumour, atypical anal sac adenocarcinoma, fibrothecoma, cutaneous mast cell tumour and transmissible venereal tumour were the tumours identified and ...
Mesfin Mathewos +2 more
wiley +1 more source
Kisspeptin as a test of hypothalamic dysfunction in pubertal and reproductive disorders
Abstract The hypothalamic–pituitary–gonadal axis is regulated by the gonadotropin‐releasing hormone pulse generator in the hypothalamus. This is comprised of neurons that secrete kisspeptin in a pulsatile manner to stimulate the release of GnRH, and, in turn, downstream gonadotropins from the pituitary gland, and subsequently sex steroids and ...
Aureliane C. S. Pierret +5 more
wiley +1 more source
Two restraining devices in connection to surgical castration with or without local anesthesia: effects on piglet stress. [PDF]
Hokkanen AH +7 more
europepmc +1 more source
Luteinizing hormone receptor knockout mouse: What has it taught us?
Abstract Luteinizing hormone (LH), along with its agonist choriongonadotropin (hCG) in humans, is the key hormone responsible for the tropic regulation of the gonadal function. LH and hCG act through their cognate receptor, the luteinizing hormone/choriongonadotropin receptor (LHCGR; more appropriately LHR in rodents lacking CG), located in the testis ...
Ilpo T. Huhtaniemi
wiley +1 more source
Behavioral Assessment Reveals GnRH Immunocastration as a Better Alternative to Surgical Castration. [PDF]
Lin L +8 more
europepmc +1 more source
Abstract Background Despite growing concerns about antimicrobial resistance, prophylactic antimicrobials continue to be routinely administered in many procedures, including dental extractions. Further evidence‐based research is needed on whether their use influences post‐operative complication rates.
Marlies Schnierer +4 more
wiley +1 more source
Effects of administering local anesthesia immediately before surgical castration on indicators of pain and discomfort of beef calves. [PDF]
Bernier AF +3 more
europepmc +1 more source
Why Is MS a More Frequent Complication of EBV Infection in Females?
ABSTRACT Multiple sclerosis (MS) is a T helper (Th) cell‐mediated disease that targets central nervous system (CNS) white matter. This disease affects three times more females than males. For many years, the etiology of MS was not well understood and the exact nature of the autoimmune reaction was speculative.
Shannon E. Dunn +2 more
wiley +1 more source
Kidney size is sex‐dimorphic and regulated by androgens in adult humans and mice. Male mice lacking the main testosterone‐producing enzyme HSD17B3 had reduced testosterone during a short fetal time window, leading to reduced size of kidneys in adults, which were not responsive to high adult testosterone.
Arttu Junnila +14 more
wiley +1 more source

