Results 211 to 220 of about 34,602 (289)
Targeting Tumor Stroma: Current Challenges and Future Directions
Figure 1. Mechanism of ECM reprogramming. Cancer‐associated fibroblasts (CAFs), cancer‐associated macrophages (CAMs), and other mesenchymal cells alter the ECM composition and increase its stiffness by depositing matrix components such as collagen and hyaluronic acid, and secreting cross‐linking agents like lysyl oxidase homolog 2 (LOXL2).
Siwei Wang +7 more
wiley +1 more source
Nanocarrier-mediated delivery of α-mangostin for non-surgical castration of male animals. [PDF]
Yostawonkul J +10 more
europepmc +1 more source
ABSTRACT Background Prostate cancer significantly impacts not only the individuals diagnosed but also their partners, who frequently undertake extensive caregiving responsibilities. Despite their crucial role, the experiences and needs of partners remain underrepresented in cancer care literature and policy, particularly in Ireland.
Seidu Mumuni +2 more
wiley +1 more source
Abstract Marine cone snails produce a diverse array of bioactive peptides, known as conotoxins, in their venom. Given their high target potency and specificity, conotoxins are attractive compounds for the development of precision research tools and pharmacological agents.
Celeste M. Hackney +12 more
wiley +1 more source
Evaluation of Loss of the Y Chromosome in Peripheral Blood as a Biomarker for Prostate Cancer
ABSTRACT Background Prostate cancer (PCa) is the most common malignant tumor in men, but the widely used prostate‐specific antigen (PSA) test has limited diagnostic accuracy. Research proposes that the loss of the Y chromosome (LOY) may affect the occurrence and development of prostate cancer, aiming to assess its potential as a diagnostic biomarker to
Jun Lu +10 more
wiley +1 more source
ABSTRACT Background Methyl Methanesulfonate‐Sensitivity Protein 22‐Like (MMS22L) plays a key role in homology‐directed DNA repair, and experimental models have shown that its loss confers sensitivity to Poly (ADP‐ribose) polymerase inhibitors (PARPi).
Mayuko Kanayama +12 more
wiley +1 more source
ABSTRACT Background To compare choline PET‐CT and PSMA PET‐CT in a cohort of patients with high‐risk localized prostate cancer, assessing the diagnostic capacity of both tests. whose therapeutic approach could be modified based on the results. Methods An observational study was conducted in 116 patients with high‐risk prostate cancer between January ...
M. A. Tárraga‐Honrubia +5 more
wiley +1 more source
Cytological and Pathological Characterization of Canine Neoplasm in and Around Bishoftu, Ethiopia
This study characterizes dog tumours cytologically and histopathologically in and around Bishoftu town. Mammary gland adenocarcinoma, papillary mammary adenocarcinoma, carcinoma–mixed type, Sertoli cell tumour, atypical anal sac adenocarcinoma, fibrothecoma, cutaneous mast cell tumour and transmissible venereal tumour were the tumours identified and ...
Mesfin Mathewos +2 more
wiley +1 more source

