Animal Cells and Systems, 2018 Androgen deprivation therapy, also known as chemical castration, has been used as an adjunct to psychotherapy for sex offenders. Goserelin and bicalutamide are drugs used for chemical castration.
Jin-Hee Han +10 more
doaj +1 more source
Czech Journal of Animal Science, 2015 The effect of surgical castration with local anesthesia using lidocaine on neopterin, biopterin, and cortisol blood plasma concentrations in piglets was studied.
P. Maršálek +3 more
doaj +1 more source
Identification of LIMK2 as a therapeutic target in castration resistant prostate cancer [PDF]
, 2019 This study identified LIMK2 kinase as a disease-specific target in castration resistant prostate cancer (CRPC) pathogenesis, which is upregulated in response to androgen deprivation therapy, the current standard of treatment for prostate cancer. Surgical
Broman, Meaghan M. +13 more
core +1 more source
Human phosphodiesterase 4D7 (PDE4D7) expression is increased in TMPRSS2-ERG positive primary prostate cancer and independently adds to a reduced risk of post-surgical disease progression [PDF]
, 2015 background: There is an acute need to uncover biomarkers that reflect the molecular pathologies, underpinning prostate cancer progression and poor patient outcome.
Baillie, G. S. +12 more
core +1 more source
A Case Report of Self-Inflicted Surgical Castration
Urogenital Tract Infection, 2023 Religious beliefs are a very significant part of one’s life. We report the case of a strongly religious man who sought to remove his testicles. After enlisting in the military, the man had a surgical castration performed on him while on vacation from military service.
Koo Han Yoo, Sung-Goo Chang
openaire +2 more sources
Effect of antiandrogen flutamide on measures of hepatic regeneration in rats [PDF]
, 1989 Male rat liver undergoes a process of demasculinization during hepatic regeneration following partial hepatectomy. The possibility that antiandrogens might potentiate this demasculinization process and in so doing augment the hepatic regenerative ...
A Francavilla +36 more
core +1 more source
BMC Genomics, 2022 Background Salivary gland (SMG) degeneration and dysfunction are common symptoms that occur after sex hormone deprivation, but the underlying mechanisms remain largely unknown.
Xingfa Han +10 more
doaj +1 more source
The Transitioning of Jewish Biomedical Law: Rhetorical and Practical Shifts in Halakhic Discourse on Sex-Change Surgery [PDF]
, 2016 This article examines discourse dynamics in Jewish law on sex-change surgery (SCS) and, in general, transitioning between genders. Orthodox medical ethics has moved beyond the abstract condemnation of SCS to the design of practical rules for transsexuals
Hillel Gray
core +1 more source
Physiology and behavior of pigs before and after castration: effects of two topical anesthetics
Animal, 2010 Surgical castration of male piglets is a common management practice conducted on commercial swine farms to prevent the occurrence of boar taint and aggressive behavior.
M.A. Sutherland +3 more
doaj +1 more source
Hematologic Toxicity of Concurrent Administration of Radium-223 and Next-generation Antiandrogen Therapies. [PDF]
, 2017 PURPOSE/OBJECTIVES: Radium-223 is a first-in-class radiopharmaceutical recently approved for the treatment of castration-resistant prostate cancer in patients with symptomatic bone metastases.
Basch +20 more
core +2 more sources