Results 11 to 20 of about 591 (205)
Long-term Surgical and Chemical Castration Deteriorates Memory Function Through Downregulation of PKA/CREB/BDNF and c-Raf/MEK/ERK Pathways in Hippocampus [PDF]
Purpose Goserelin is a drug used for chemical castration. In a rat model, we investigated whether surgical and chemical castration affected memory ability through the protein kinase A (PKA)/cyclic adenosine monophosphate response element-binding protein (
Mal-Soon Shin +8 more
doaj +1 more source
Utilization and Outcomes of Surgical Castration in Comparison to Medical Castration in Metastatic Prostate Cancer [PDF]
288 Background: Androgen deprivation therapy (ADT) is the gold standard for metastatic prostate cancer (mPC) which can be achieved either by surgical or medical castration (SC, MC). In this study we evaluate the trends of utilization of SC and also assess survival difference compared to MC.
Rohan Garje +6 more
openaire +2 more sources
Effectof Castration on Some Immunological Aspects in Male Albino Rat [PDF]
The current study aimed to evaluate the effect of surgical and chemical castration on some immunological aspects in adult male albino rats. A total number of forty adult male albino rats weighing 220±20 g and averaging 4 months old were used.
S. M. Habak +3 more
doaj +1 more source
Background. Most patients with metastatic prostate cancer are endocrinologically treated with LHRH agonist, but finally castration-refractory and hormone-refractory cancers occur.
Masayoshi Zaitsu +7 more
doaj +1 more source
This study assessed the efficacy of pre-operative injected lignocaine and peri-operative topical vapocoolant spray, administered as most practical for incorporation into routine calf castration procedures.
Dominique Van der Saag +4 more
doaj +1 more source
Androgen deprivation therapy, also known as chemical castration, has been used as an adjunct to psychotherapy for sex offenders. Goserelin and bicalutamide are drugs used for chemical castration.
Jin-Hee Han +10 more
doaj +1 more source
The effect of surgical castration with local anesthesia using lidocaine on neopterin, biopterin, and cortisol blood plasma concentrations in piglets was studied.
P. Maršálek +3 more
doaj +1 more source
Pain alleviation associated with surgical castration of piglets is a debated welfare issue. The present study compares the effect of different protocols involving analgesia and/or anaesthesia or sedation suitable under field conditions, with the aim to ...
Annalisa Scollo +5 more
doaj +1 more source
Background Chemical castration of male animals is an alternative to surgical castration for inducing azoospermia, consequent sterility. Intra-testicular injection of zinc gluconate has been used for chemical castration in several animal species. However,
Mohamed A. Hamed +7 more
doaj +1 more source
Murine Prostate Micro-dissection and Surgical Castration [PDF]
Mouse models are used extensively to study prostate cancer and other diseases. The mouse is an excellent model with which to study the prostate and has been used as a surrogate for discoveries in human prostate development and disease. Prostate micro-dissection allows consistent study of lobe-specific prostate anatomy, histology, and cellular ...
Kenneth C, Valkenburg +2 more
openaire +2 more sources

