Results 11 to 20 of about 591 (205)

Long-term Surgical and Chemical Castration Deteriorates Memory Function Through Downregulation of PKA/CREB/BDNF and c-Raf/MEK/ERK Pathways in Hippocampus [PDF]

open access: yesInternational Neurourology Journal, 2019
Purpose Goserelin is a drug used for chemical castration. In a rat model, we investigated whether surgical and chemical castration affected memory ability through the protein kinase A (PKA)/cyclic adenosine monophosphate response element-binding protein (
Mal-Soon Shin   +8 more
doaj   +1 more source

Utilization and Outcomes of Surgical Castration in Comparison to Medical Castration in Metastatic Prostate Cancer [PDF]

open access: yesClinical Genitourinary Cancer, 2019
288 Background: Androgen deprivation therapy (ADT) is the gold standard for metastatic prostate cancer (mPC) which can be achieved either by surgical or medical castration (SC, MC). In this study we evaluate the trends of utilization of SC and also assess survival difference compared to MC.
Rohan Garje   +6 more
openaire   +2 more sources

Effectof Castration on Some Immunological Aspects in Male Albino Rat [PDF]

open access: yesBenha Veterinary Medical Journal, 2018
The current study aimed to evaluate the effect of surgical and chemical castration on some immunological aspects in adult male albino rats. A total number of forty adult male albino rats weighing 220±20 g and averaging 4 months old were used.
S. M. Habak   +3 more
doaj   +1 more source

Surgical Castration in Hormone-Refractory Metastatic Prostate Cancer Patients Can Be an Alternative for Medical Castration

open access: yesAdvances in Urology, 2012
Background. Most patients with metastatic prostate cancer are endocrinologically treated with LHRH agonist, but finally castration-refractory and hormone-refractory cancers occur.
Masayoshi Zaitsu   +7 more
doaj   +1 more source

Effect of Lignocaine and a Topical Vapocoolant Spray on Pain Response during Surgical Castration of Beef Calves

open access: yesAnimals, 2019
This study assessed the efficacy of pre-operative injected lignocaine and peri-operative topical vapocoolant spray, administered as most practical for incorporation into routine calf castration procedures.
Dominique Van der Saag   +4 more
doaj   +1 more source

Long-term chemical castration induces depressive symptoms by suppressing serotonin expression in rats

open access: yesAnimal Cells and Systems, 2018
Androgen deprivation therapy, also known as chemical castration, has been used as an adjunct to psychotherapy for sex offenders. Goserelin and bicalutamide are drugs used for chemical castration.
Jin-Hee Han   +10 more
doaj   +1 more source

Concentrations of neopterin, biopterin, and cortisol associated with surgical castration of piglets with lidocaine

open access: yesCzech Journal of Animal Science, 2015
The effect of surgical castration with local anesthesia using lidocaine on neopterin, biopterin, and cortisol blood plasma concentrations in piglets was studied.
P. Maršálek   +3 more
doaj   +1 more source

Analgesia and/or anaesthesia during piglet castration – part I: efficacy of farm protocols in pain management

open access: yesItalian Journal of Animal Science, 2021
Pain alleviation associated with surgical castration of piglets is a debated welfare issue. The present study compares the effect of different protocols involving analgesia and/or anaesthesia or sedation suitable under field conditions, with the aim to ...
Annalisa Scollo   +5 more
doaj   +1 more source

Evaluation of chemical castration using intra-testicular injection of zinc gluconate into the testis of the male donkey versus surgical castration: antimullerian hormone as an endpoint marker

open access: yesBMC Veterinary Research, 2023
Background Chemical castration of male animals is an alternative to surgical castration for inducing azoospermia, consequent sterility. Intra-testicular injection of zinc gluconate has been used for chemical castration in several animal species. However,
Mohamed A. Hamed   +7 more
doaj   +1 more source

Murine Prostate Micro-dissection and Surgical Castration [PDF]

open access: yesJournal of Visualized Experiments, 2016
Mouse models are used extensively to study prostate cancer and other diseases. The mouse is an excellent model with which to study the prostate and has been used as a surrogate for discoveries in human prostate development and disease. Prostate micro-dissection allows consistent study of lobe-specific prostate anatomy, histology, and cellular ...
Kenneth C, Valkenburg   +2 more
openaire   +2 more sources

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