Results 201 to 210 of about 1,019,468 (263)

Various dimensions of sexual self‐concept in middle‐aged men after vasectomy: a matched analysis

open access: yesBJU International, Volume 138, Issue 3, Page 438-448, September 2026.
Objectives To compare men with and without vasectomy across four dimensions of sexual self‐concept—toughness, body image, sexual self‐esteem, and perceived pressure with regard to sexuality—and to examine differences in sexual behaviour and psychosocial factors.
Lilly J. Schmalbrock   +9 more
wiley   +1 more source

Intermediate clinical endpoints as surrogates for overall survival after salvage prostatectomy

open access: yesBJU International, Volume 138, Issue 3, Page 430-437, September 2026.
Objectives To evaluate biochemical recurrence‐free survival (BRFS) and metastasis‐free survival (MFS) as potential intermediate clinical endpoints (ICEs) for overall survival (OS) in patients undergoing salvage radical prostatectomy (sRP). Patients and Methods Evaluable patients were selected from a retrospective dataset, resulting in a cohort of 879 ...
Navid Roessler   +22 more
wiley   +1 more source

Hypericin Suppresses Liver Cancer Through Autophagic Degradation of AKT and Eliciting Antitumor Immune Response

open access: yesCancer Science, Volume 117, Issue 9, Page 2567-2585, September 2026.
Hypericin induces autophagic AKT degradation by promoting AKT‐HSPA5 interaction in an S473 phosphorylation‐dependent manner, suppressing HCC growth. It enhances CD8+ T cell‐mediated antitumor immunity and synergizes with anti‐PD‐L1 therapy, showing favorable safety for HCC treatment. ABSTRACT Hepatocellular carcinoma (HCC) is the most prevalent primary
Sien Ma   +12 more
wiley   +1 more source

Integrated Engineering of CAR‐T Cells for Solid Tumours

open access: yesCell Proliferation, Volume 59, Issue 9, September 2026.
Solid tumours pose multifactorial barriers including antigen heterogeneity, immunosuppressive microenvironment, and poor T‐cell trafficking, limiting CAR‐T efficacy compared to hematologic malignancies. Integrated engineering strategies are essential, combining logic‐gated receptors for precision, metabolic‐epigenetic reprogramming for resilience, and ...
Chao Yang   +5 more
wiley   +1 more source

Effects of surgical timing on inflammatory responses, oxidative stress, and immune modulation in Wagyu calves following castration. [PDF]

open access: yesBMC Vet Res
Promsut W   +7 more
europepmc   +1 more source

Reliability of three scoring systems for assessing quality of anaesthetic induction in horses

open access: yesEquine Veterinary Journal, Volume 58, Issue 5, Page 1199-1206, September 2026.
Abstract Background Several induction quality scoring systems (IQSS) have been described to evaluate drugs and risk factors of this anaesthetic period in horses, but no attempts to compare their reliability have been performed. Objectives To elucidate the reliability of three IQSS: the visual analogue scale (VAS), a simple descriptive scale (SDS), and ...
Marta Villalba‐Díez   +4 more
wiley   +1 more source

Physiological and behavioural effects of continuous remifentanil‐xylazine administration in donkeys

open access: yesEquine Veterinary Journal, Volume 58, Issue 5, Page 1390-1395, September 2026.
Abstract Background Remifentanil and xylazine are used as continuous infusions to facilitate standing surgery in horses. Their use for this purpose has not been reported in donkeys. Objectives To evaluate the behavioural, sedative, and cardiorespiratory effects of continuous intravenous infusion of remifentanil and xylazine in donkeys. Study Design Non‐
Kássia Fernanda Araújo Damasceno   +6 more
wiley   +1 more source

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