Results 261 to 270 of about 2,236,655 (350)

Effects of Different Endoscopic Treatment Methods on Bleeding Complications in Pedunculated Colorectal Polyps. [PDF]

open access: yesSurg Laparosc Endosc Percutan Tech
Li X   +6 more
europepmc   +1 more source

Hemophilia A: An Ideal Disease for Prenatal Therapy

open access: yesPrenatal Diagnosis, EarlyView.
ABSTRACT Hemophilia A (HA) is the most common inherited coagulation defect. Current state‐of‐the‐art treatment consists of frequent administration of prophylactic infusions of coagulation factor VIII (FVIII) protein or bispecific antibodies that replace the cofactor function of FVIIIa to maintain hemostasis. However, these treatments are far from ideal,
Christopher D. Porada   +2 more
wiley   +1 more source

Micro‐ and nanomotors in biomedical applications

open access: yesResponsive Materials, EarlyView.
Micro‐ and nanomotors (MNMs), as autonomous devices converting chemical or external energy into mechanical propulsion, have emerged as transformative drug delivery platforms in biomedicine. This review systematically outlines the design principles governing MNMs' propulsion and operation, highlights the applications of MNMs in disease treatment, and ...
Xiangyu Meng, Yuqi Tang, Quan Li
wiley   +1 more source

Acute epidural hematoma extending bilaterally and infratentorially: illustrative case. [PDF]

open access: yesJ Neurosurg Case Lessons
Aoki T   +7 more
europepmc   +1 more source

Advancing Sensory Modulation Wound Healing of Bionic Polymer Microneedle Patch

open access: yesSensory Neuroscience, EarlyView.
The complex etiology and pathogenesis of chronic wounds leading to a high rate of recurrence. Microneedle based transdermal drug delivery systems have emerged as new solutions in the field of drug delivery. Researchers developed polymer indwelling MN through a combined manufacturing strategy involving formwork replication and 3D transfer printing. With
Shana Zhang, Bingbing Gao
wiley   +1 more source

Nanoparticle Therapeutics in Clinical Perspective: Classification, Marketed Products, and Regulatory Landscape

open access: yesSmall, EarlyView.
This review presents a detailed overview of clinically approved nanoparticle therapeutics, classifying them by type and discussing their unique advantages in drug delivery. It highlights regulatory challenges across global markets and emphasizes the need for adaptive approval pathways.
Nimeet Desai   +5 more
wiley   +1 more source

An Integrated Method to Evaluate the Treatment Efficacy and Immunogenicity of B‐Cell Acute Lymphoblastic Leukemia Therapeutic Enzyme Formulations

open access: yesSmall Methods, EarlyView.
This work presents an integrated set of methods to evaluate the efficacy of asparaginase formulations against B‐cell Acute Lymphoblastic Leukemia (ALL) in mice, including the establishment of an ALL murine model, an amino acid depletion study using high‐performance liquid chromatography (HPLC), and comprehensive assessment of antibody production ...
Julien Santelli   +6 more
wiley   +1 more source

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