Results 291 to 300 of about 2,236,655 (350)

A Biodegradable Hemostatic Gelatin/Polycaprolactone Composite for Surgical Hemostasis

Annals of Plastic Surgery, 2017
Massive bleeding is the leading cause of battlefield-related deaths and the second leading cause of deaths in civilian trauma centers. One of the challenges of managing severe wounds is the need to promote hemostasis as quickly as possible, which can be achieved by using hemostatic dressings.
Niann-Tzyy Dai, Yun-Lung Fang, Keng-Yen Fu, Nien-Chi Huang, Tzu-Wei Lu, Pai-Shan Hsieh, Lien-Guo Dai, Yu-Min Hung, Shyi-Gen Chen, Tim-Mo Chen   +9 more
openaire   +3 more sources

Surgical hemostasis

Journal of Neurosurgery, 1979
✓ Every surgical procedure taxes the hemostatic defenses of the patient. If his hemostatic mechanism is sound, he is unlikely to have a bleeding problem during or after an operation, unless, of course, a suture or clip slips off. Two classes of patients do present bleeding problems to the surgeon.
C A, Owen, E J, Bowie
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Topical Recombinant Human Thrombin in Surgical Hemostasis

Seminars in Thrombosis and Hemostasis, 2010
The achievement of hemostasis is paramount, and good operative practice is crucial to all surgical procedures. Intraoperative hemostasis is usually achieved through suture ligation for larger vessels and electrocautery of smaller vessels; certain cases, however, are not amenable to these techniques, especially when there is diffuse raw surface bleeding.
Christopher D. Anderson, William C. Chapman, Lyndsey J. Bowman   +2 more
openaire   +3 more sources

Management of surgical hemostasis: topical agents.

Vascular, 2008
Intraoperative control of bleeding during any surgical procedure is vital for achieving a positive patient outcome. Hemostasis can be achieved through practical and effective systemic or topical approaches. A variety of hemostatic methods can be employed, ranging from simple manual pressure application with one finger to electrical tissue cauterization,
Jeffrey H. Lawson, Hardean E. Achneck, Bantayehu Sileshi   +2 more
openaire   +4 more sources

Fibrocaps for surgical hemostasis: two randomized, controlled phase II trials

Journal of Surgical Research, 2015
Fibrocaps, a ready-to-use, dry-powder fibrin sealant containing human plasma-derived thrombin and fibrinogen, is being developed as an adjunct for surgical hemostasis.Safety and efficacy of Fibrocaps applied directly or by spray device, in combination with gelatin sponge, was compared with that of gelatin sponge-alone in two randomized, single-blind ...
Verhoef, C., Singla, N., Moneta, G., Muir, W., Rijken, A., Lockstadt, H., Wilt, J.H.W. de, O-Yurvati, A., Zuckerman, L.A., Frohna, P., Porte, R.J.   +10 more
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Surgical Hemostasis With a Factor XI-Containing Concentrate

JAMA: The Journal of the American Medical Association, 1974
In factor XI deficiency, plasma infusions remain the primary source of replacement but often prove inadequate in a hemorrhagic crisis. A large amount of factor XI was found to be present in a prothrombin-containing concentrate. This was used when a severely factor XI-deficient patient required extensive hip surgery, during which excellent surgical ...
Rodger L. Bick, Thompson Adams, Kenneth Radack   +2 more
openaire   +4 more sources

A review of three stand-alone topical thrombins for surgical hemostasis

Clinical Therapeutics, 2009
Topical thrombins are active hemostatic agents that can be used to minimize blood loss during surgery. Before 2007, the only topical thrombins available were derived from bovine plasma. Antibody formation to bovine thrombin and/or factor V, with subsequent risk of cross-reactivity with human factor V, and hemorrhagic complications associated with human
Cheng, Christine M., Meyer-Massetti, Carla, Kayser, Steven R.   +2 more
openaire   +5 more sources

Hemostasis, Surgical Bleeding, and Transfusion

Equine Surgery, 2012
M. Mudge
openaire   +2 more sources

New and potential uses of fibrin sealants as an adjunct to surgical hemostasis

The American Journal of Surgery, 2001
Commercially prepared fibrin sealants have been available in Europe and Japan for many years. However, current formulations are exclusively two-component, liquid fibrin sealants, and delivery devices are rather rudimentary. To date, this has had the effect of limiting the number of clinical applications that make use of fibrin sealants.
Mark R. Jackson
openaire   +4 more sources

Achieving Hemostasis in the Surgical Field [PDF]

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 2009
Hemostatic mechanisms are an integral part of the human physiology. Traditionally divided into intrinsic and extrinsic arms, the coagulation cascade converges, through the interactions of many different factors, at a common element—thrombin. As a consequence, a number of different agents have been developed to supplement this common, critical step to ...
Bradley A. Boucher, Oren Traub
openaire   +2 more sources