Results 61 to 70 of about 4,737,260 (339)
Surgical Margin Status after Breast Conservation Surgery at Aga Khan University Hospital Nairobi
The Annals of African Surgery, 2018 Background: The conservation of the breast in a woman after diagnosis of breast cancer plays a vital role in the overall management of the patient. While the cosmetic outcome enhances the patients’ self-image, assurance of clear margins is essential in ...
Riogi B, Wasike R
doaj
Wide Surgical Margin Improves the Outcome for Patients with Gastrointestinal Stromal Tumors (GISTs)
World Journal of Surgery, 2018 BackgroundSurgical resection is still the main treatment for gastrointestinal stromal tumor (GIST), and R0 excision, regardless of surgical margins, is considered sufficient.MethodsA cohort of 79 consecutive GIST cases treated at the Karolinska ...
J. Åhlén +5 more
semanticscholar +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Constant Rate Approximate Maximum Margin Algorithms
, 2006 We present a new class of perceptron-like algorithms with margin in which the “effective” learning rate, defined as the ratio of the learning rate to the length of the weight vector, remains constant. We prove that the new algorithms converge in a finite
Shawe-Taylor, John, Tsampouka, Petroula
core +2 more sources
Surgical Margin Status after Breast Conservation Surgery at Aga Khan University Hospital Nairobi
The Annals of African Surgery, 2014 Background: The conservation of the breast in a woman after diagnosis of breast cancer plays a vital role in the overall management of the patient. While the cosmetic outcome enhances the patients’ self-image, assurance of clear margins is essential in ...
Riogi B, Wasike R
doaj
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Factors affecting surgical margin positivity in robotic assisted radical prostatectomy [PDF]
, 2017 Objectives: After radical prostatectomy, surgical margin positivity is an important indicator of biochemical recurrence and progression. In our study we want to compare the surgical margin positivity rates for retropubic radical prostatectomy (RRP) and ...
Mustafa Yuksel +5 more
core +1 more source
A review of methods of intraoperative margin assessment in breast conserving surgery
Nowotwory, 2021 Breast conserving therapy is the primary treatment modality in early-stage breast cancer patients. Despite the development of methods for the intraoperative assessment of tumor margins, 20–30% of patients still require re-resection due to postoperative ...
Tomasz Sachańbiński, Barbara Radecka
doaj +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
The surgical resection margin [PDF]
Head & Neck Oncology, 2009 In the treatment of cancer the fundamental surgical goal is to remove all local malignant disease and leave no residual malignant cells. Studies have demonstrated the benefit of achieving negative resection margins in terms of disease free local recurrence and overall survival.
openaire +1 more source