Results 51 to 60 of about 109,217 (248)

Feasibility and Safety of Outpatient Lumbar Microscopic Discectomy in a Developing Country [PDF]

open access: yesAsian Spine Journal, 2019
Study Design Prospective study. Purpose To verify the feasibility and safety of outpatient microscopic lumbar discectomy (MLD) in a developing country. Overview of Literature Outpatient MLD is advantageous in terms of cost effectiveness and avoidance of ...
Ashish Jaiswal   +3 more
doaj   +1 more source

Surgical and Minimally Invasive Cosmetic Procedures Among Persons With Body Dysmorphic Disorder [PDF]

open access: yesAnnals of Plastic Surgery, 2010
Persons with body dysmorphic disorder (BDD) frequently seek surgical and minimally invasive (MI) treatments to improve their appearance, but few studies have evaluated patient characteristics and outcomes. Surgical/MI treatment histories of 200 persons with BDD were cross-sectionally/retrospectively evaluated.
William Menard   +2 more
openaire   +2 more sources

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

The ACCEPTance of automation: refining circulating tumor cells enumeration for improved metastatic colorectal cancer prognosis

open access: yesMolecular Oncology, EarlyView.
This study highlights the potential of automated enumeration using the ACCEPT software to refine circulating tumor cell (CTC) detection in metastatic colorectal cancer (mCRC). The automated method demonstrates improved accuracy and reduced variability compared to the manual approach.
Michela De Meo   +6 more
wiley   +1 more source

Facial Rejuvenation Enhancing Cheek Lift

open access: yesArchives of Plastic Surgery, 2017
Supported by recent literature on the signs of aging of the middle and lower face, our clinical research has documented a loss of volume of the deep structural components of the central face and a progressive descent of the nasolabial fat and the jowl ...
Philippe Bellity, Jonathan Bellity
doaj   +1 more source

Is robot-assisted laparoscopic myomectomy limited in multiple myomas?: a feasibility for ten or more myomas [PDF]

open access: yesObstetrics & Gynecology Science, 2018
ObjectiveTo evaluate the feasibility of robot-assisted laparoscopic myomectomy in multiple myomas over 10.MethodsA retrospective study was conducted for 662 patients who underwent robot-assisted laparoscopic myomectomy and open myomectomy by a single ...
Hyunkyung Kim   +7 more
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

A guide to reactive oxygen species in tumour hypoxia: measurement and therapeutic implications

open access: yesMolecular Oncology, EarlyView.
Hypoxia reshapes tumour redox landscapes by altering compartmental ROS production (mitochondria, NOX, ER, peroxisomes). Accurate interpretation requires oxygen‐contextualised measurement (live biosensors, chemical probes, EPR, LC–MS) and awareness of artefacts (reoxygenation, probe specificity).
Lina Hacker   +3 more
wiley   +1 more source

Blocking the voltage‐gated sodium channel hNav1.5 as a novel pH‐dependent mechanism of action for tamoxifen

open access: yesFEBS Open Bio, EarlyView.
Patch‐clamp recordings revealed that tamoxifen inhibits voltage‐gated sodium channels, especially under acidic conditions, both common in metastatic cancer cells. These effects may explain certain antitumor properties of tamoxifen, highlighting a novel mechanism of action beyond its known endocrine effects.
Karl Josef Föhr   +5 more
wiley   +1 more source

Clinical Assessment of Open Flap Debridement Using Magnifying Loupes and Surgical Operating Microscope: A Split-Mouth Randomized Controlled Clinical Trial

open access: yesFrontiers in Dentistry
Objectives: To overcome the drawbacks of the conventional flap surgery, newer surgical techniques like minimally invasive surgery were evolved to optimize the primary closure of the flap.
Jaswitha Vintha   +5 more
doaj   +1 more source

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