Results 51 to 60 of about 429,608 (293)

Single cis‐elements in brassinosteroid‐induced upregulated genes are insufficient to recruit both redox states of the BIL1/BZR1 DNA‐binding domain

FEBS Letters, EarlyView.
Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki, Masae Ohtsuka, Takeshi Nakano, Masaru Tanokura, Takuya Miyakawa   +4 more
wiley   +1 more source

VERTEBRAL HYDATIDOSIS: BIBLIOGRAPHICAL REVIEW AND CLINICAL CASE REPORT

Coluna/Columna
We will present a literature review of the vertebral location of hydatidosis. It is a rare, locally aggressive condition with a high recurrence rate that requires clinical treatment (antihelminthic drugs) and surgery, with decompression of the spinal ...
Juan Manuel Velasco, Santiago Sapriza, Nicolás Galli, Fernando Garcìa   +3 more
doaj   +1 more source

Incidence of Operating Room Fires During Hand Surgical Procedures.

The archives of bone and joint surgery, 2021
The purpose of the present study is to report the incidence of operating room fires during hand surgical procedures.The clinic and OR electronic medical records of seven fellowship-trained orthopedic hand surgeons at a single, large practice were retrospectively reviewed.
Lili Schindelar, Pedro K. Beredjiklian, Kevin F. Lutsky, Daniel A. Seigerman, Chistopher M Jones, Brian Katt   +5 more
openaire   +3 more sources

Clinical review: Can we predict which patients are at risk of complications following surgery? [PDF]

, 2013
There are a vast number of operations carried out every year, with a small proportion of patients being at highest risk of mortality and morbidity. There has been considerable work to try and identify these high-risk patients.
Hamilton, M, Shah, N
core   +1 more source

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

FEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona, Carlo M. Bergamini, Carlo Ferrari, Stefano Volinia, Nicoletta Bianchi   +4 more
wiley   +1 more source

Challenges in evaluating surgical innovation [PDF]

, 2009
Research on surgical interventions is associated with several methodological and practical challenges of which few, if any, apply only to surgery. However, surgical evaluation is especially demanding because many of these challenges coincide.
Blazeby, Jane M, Boutron, Isabelle, Clavein, Pierre-Alain, Cook, Jonathan Alistair, Ergina, Patrick L, Reeves, Barnaby C, Seiler, Christoph M   +6 more
core   +1 more source

Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1

FEBS Letters, EarlyView.
Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri, Andrea Lapucci, Giuseppe Orsomando, Nadia Raffaelli, Alberto Chiarugi, Daniela Buonvicino   +5 more
wiley   +1 more source

Tertiary blast injury to the intestines [PDF]

Vojnosanitetski Pregled, 2005
Background. To present the first case of the tertiary blast injury to the intestine, and the tertiary blast injury in general. Case report. A parachutist of the Army of Serbia and Montenegro was injured when descended from the 1 200m height by parachute ...
Ignjatović Dragan, Ćuk Vladimir, Jevtić Miodrag   +2 more
doaj   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

FEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur, Brian Acquaviva, Baylee A. Smith, Nathan Walker, Isabella Walter, Matthew L. Wohlever   +5 more
wiley   +1 more source

Patients' inability to perform a preoperative cardiopulmonary exercise test or demonstrate an anaerobic threshold is associated with inferior outcomes after major colorectal surgery. [PDF]

, 2013
BACKGROUND: Surgical patients with poor functional capacity, determined by oxygen consumption at anaerobic threshold (AT) during cardiopulmonary exercise testing (CPET), experience longer hospital stays and worse short- and medium-term survival. However,
Buck, C.P. Challand, C.W. Lai, Carli, Carlisle, Challand, Chase, Copeland, G Minto, J.R. Sneyd, K.B. Hosie, Mayo, Older, Older, Pearse, R.A. Struthers, S Creanor, Shoemaker, Shoemaker, Swart, Tekkis, Visser, Wilson   +22 more
core   +3 more sources