Results 61 to 70 of about 2,951,344 (295)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

A safe teaching protocol of LRP (Laparoscopic Radical Prostatectomy)

International Brazilian Journal of Urology
Purpose The LRP has a steep learning curve to obtain proficiency during which patient safety may be compromised. We present an adapted modular training system which purpose to optimize the learning curve and perform a safe surgery. Materials and Methods
Marcos Tobias-Machado, Cristiano Linck Pazeto, Oseas Castro Neves-Neto, Igor Nunes-Silva, Hamilton de Campos Zampolli   +4 more
doaj   +1 more source

Considerations for the Management of Medial Orbital Wall Blowout Fracture

Archives of Plastic Surgery, 2016
Recently, diagnoses of and operations for medial orbital blowout fracture have increased because of the development of imaging technology. In this article, the authors review the literature, and overview the accumulated knowledge about the orbital ...
Yong-Ha Kim, Youngsoo Park, Kyu Jin Chung   +2 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Impact of time from biopsy to surgery on complications, functional and oncologic outcomes following radical prostatectomy

International Brazilian Journal of Urology
Introduction: To determine the impact of time from biopsy to surgery on outcomes following radical prostatectomy (RP) as the optimal interval between prostate biopsy and RP is unknown.
Mary E. Westerman, Vidit Sharma, George C. Bailey, Stephen A. Boorjian, Igor Frank, Matthew T. Gettman, R. Houston Thompson, Matthew K. Tollefson, Robert Jeffrey Karnes   +8 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Presentation and surgery outcomes in elderly with pheocromocytoma: a comparative analysis with young patients

International Brazilian Journal of Urology
Purpose: To evaluate the presentation and early surgical outcomes of elderly patients undergoing adrenalectomy for phaeochromocytoma. Patients and Methods: A retrospective search was performed of our adrenal disorders database for patients who underwent
Victor Srougi, Jose L. Chambo, Fabio Y. Tanno, Iracy S. Soares, Madson Q. Almeida, Maria A. A. Pereira, Miguel Srougi, Maria C. Fragoso   +7 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Identification of risk factors by systematic review and development of risk-adjusted models for surgical site infection [PDF]

, 2011
Background: Surgical site infections (SSIs) are complications of surgery that cause significant postoperative morbidity. SSI has been proposed as a potential indicator of the quality of care in the context of clinical governance and monitoring of the ...
Wilson, AP, Pearson, A. (Andrew), ZH Krukowski, Bruce, J, Krukowski, Zygmunt H., Gibbons, C., Pearson, A, Lamping, Donna Louise, Reeves, BC, AP Wilson, DL Lamping, J Wilson, Krukowski, ZH, Lamping, DL, J Carpenter, Krukowki, ZH, J Bruce, Carpenter, J., Gibbons, C, A Pearson, Wilson, J, Wilson, A. P. (A. Peter), BC Reeves, Reeves, B. C., Wilson, Jennie, RGN, C Gibbons, Bruce, J. (Julie), Carpenter, J   +27 more
core   +1 more source

Surgical management of the cases with both biliary and duodenal obstruction

Gastrointestinal Intervention, 2018
Endoscopic management is presently the recommended first-line of treatment for biliary strictures. However, surgery still has an important role especially for biliary obstruction (BO) with duodenal obstruction.
Yoshihiro Miyasaka, Takao Ohtsuka, Vittoria Vanessa Velasquez, Yasuhisa Mori, Kohei Nakata, Masafumi Nakamura   +5 more
doaj   +1 more source