Results 81 to 90 of about 3,094,612 (302)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

IS THE ADENOID OPERATION A JUSTIFIABLE SURGICAL PROCEDURE [PDF]

Journal of the American Medical Association, 1903
At first thought it would seem that to read a paper with this title before this Section is like raising up a man of straw and promptly proceeding to demolish it because it can make no resistance. I hope, however, to demonstrate that a paper with this title is neither untimely nor devoid of interest.
openaire   +2 more sources

The Surgical Release of Dupuytren's Contracture Using Multiple Transverse Incisions

Archives of Plastic Surgery, 2012
Dupuytren's contracture is a condition commonly encountered by hand surgeons, although it is rare in the Asian population. Various surgical procedures for Dupuytren's contracture have been reported, and the outcomes vary according to the treatment ...
Hyunjic Lee, Surak Eo, Sanghun Cho, Neil F. Jones   +3 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Transcatheter versus surgical aortic-valve replacement in high-risk patients. [PDF]

, 2011
BACKGROUND: The use of transcatheter aortic-valve replacement has been shown to reduce mortality among high-risk patients with aortic stenosis who are not candidates for surgical replacement.
Makkar, Raj R, Samir Kapadia, Dewey, Todd, Pichard, Augusto D, Mack, Michael J, Vinod H. Thourani, Duolao Wang, Smith, Craig R, Webb, John G, Babaliaros, Vasilis, Moses, Jeffrey W, D. Craig Miller, Jeffrey W. Moses, Wang, Duolao, Craig R. Smith, Mathew Williams, Todd Dewey, Miller, D Craig, Michael J. Mack, John G. Webb, William N. Anderson, Tuzcu, E Murat, Thourani, Vinod H, Raj R. Makkar, Gregory P. Fontana, Svensson, Lars G, Kapadia, Samir, E. Murat Tuzcu, Paul Corso, Martin B. Leon, Williams, Mathew, Stuart J. Pocock, Bavaria, Joseph E, MD, Howard C. Herrmann, Augusto D. Pichard, Lars G. Svensson, Pocock, Stuart J, Jodi J. Akin, Joseph E. Bavaria, Fontana, Gregory P, Akin, Jodi J, Corso, Paul, Bavaria, Joseph E, Leon, Martin B, Herrmann, Howard C, PARTNER Trial Investigators, Anderson, William N, Vasilis Babaliaros   +47 more
core   +1 more source

Reintervenciones quirúrgicas en el servicio de cirugía del hospital "Aleida Fernández Chardiet"

Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2016
Fundamento: las relaparotomías pueden ser programadas o a demanda; esta última se decide acorde a la evolución posoperatoria del enfermo, el juicio clínico del especialista en cirugía y el equipo médico de apoyo.Objetivo: caracterizar las ...
Victor Manuel Sierra Alfonso
doaj  

Estudo comparativo de retalhos tubulares de pele de ratos com dois tipos de cateter como molde

Revista do Colégio Brasileiro de Cirurgiões
OBJETIVO: A tubulização de retalhos de pele é um artifício técnico muito empregado na correção de hipospádias. Existem controvérsias quanto aos riscos e benefícios do uso de sondas para moldar a neo-uretra e promover a derivação urinária.
Antonio Henrique Rodrigues dos Passos, Fernando Costa, Lúcio Tedesco Marchese   +2 more
doaj   +1 more source

Abdominal testicular vessel distribution in human fetuses - basis for Fowler-Stephens surgery [PDF]

International Brazilian Journal of Urology
Purpose: To analyze the histology and distribution of abdominal testicular vessels in human fetuses Patients and Methods: We studied 19 fetuses (34 testes) ranging in age from 12 to 19 weeks post-conception.
Tatiana S. C. G. Benzi, Carla M. Gallo, Anneliese Fortuna, Waldemar S. Costa, Francisco J.B. Sampaio, Luciano A. Favorito   +5 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source