Results 71 to 80 of about 2,951,344 (295)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Improving parathyroid preservation in thyroidectomy: The case for near-infrared autofluorescence guidance

open access: yesJournal of the Pakistan Medical Association
Dear Editor, Thyroidectomy, once banned by the French medical society in 1850, is now a widely performed procedure. It is indicated for various thyroid pathologies, including thyroid cancer, Hurthle cell tumours, and large goiter’s that cause ...
Abdullah Azam, Faaiz Rizvi, Ushna Khan
doaj   +1 more source

Malleable Penile Prosthesis Fractures: Lessons Learned from 17 Years of Experience at a Tertiary Center in Brazil [PDF]

open access: yesInternational Brazilian Journal of Urology
Purpose: To critically evaluate the clinical presentation, imaging performance and surgical findings of malleable penile prosthesis (MPP) fractures in a high-volume tertiary center.
Manuela Horta   +10 more
doaj   +2 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Ambulatory and inpatient procedures in the United States, 1994 [PDF]

open access: yes
This report presents estimates of surgical and nonsurgical procedures performed in the United States during 1994. Data are presented by characteristics of patients, region of the country, and procedure categories for ambulatory and inpatient procedures ...

core  

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Comparative analysis between outcomes of minimally invasive gynaecological surgeries and traditional abdominal surgeries for benign gynaecological conditions

open access: yesJournal of the Pakistan Medical Association
Objective: To compare outcomes of minimally invasive gynaecological surgeries with open gynaecological surgical techniques in a low-resource setting.
Ammara Iqbal Muhammad   +4 more
doaj   +1 more source

IS THE ADENOID OPERATION A JUSTIFIABLE SURGICAL PROCEDURE [PDF]

open access: yesJournal of the American Medical Association, 1903
At first thought it would seem that to read a paper with this title before this Section is like raising up a man of straw and promptly proceeding to demolish it because it can make no resistance. I hope, however, to demonstrate that a paper with this title is neither untimely nor devoid of interest.
openaire   +2 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

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