Results 71 to 80 of about 429,608 (293)

Mitochondrial fatty acid oxidation is stimulated by red light irradiation

FEBS Letters, EarlyView.
Light at different wavelengths has distinct effects on keratinocyte viability and metabolism. UVA light abrogates metabolic fluxes. Blue and green light have no effect on metabolic fluxes, while red light enhanced oxidative phosphorylation by promoting fatty acid oxidation. Keratinocytes are the primary constituents of sunlight‐exposed epidermis.
Manuel Alejandro Herrera, Camille C. Caldeira da Silva, Maiza Von Denz, Mauricio S. Baptista, Alicia J. Kowaltowski   +4 more
wiley   +1 more source

Vacuolar transport and function of Saccharomyces cerevisiae sterol ester hydrolase Tgl1

FEBS Letters, EarlyView.
Tgl1, one of yeast sterol ester hydrolases, had been found on the lipid droplets where sterol esters are mainly stored. This study revealed that Tgl1 is transported into the vacuole depending on the ESCRT‐I–III complex, and that it exhibits intra‐vacuolar sterol ester hydrolase activity.
Takumi Nakatsuji, Kosuke Shiraishi, Chuqian Wang, Hiroya Yurimoto, Yasuyoshi Sakai, Masahide Oku   +5 more
wiley   +1 more source

A safe teaching protocol of LRP (Laparoscopic Radical Prostatectomy)

International Brazilian Journal of Urology
Purpose The LRP has a steep learning curve to obtain proficiency during which patient safety may be compromised. We present an adapted modular training system which purpose to optimize the learning curve and perform a safe surgery. Materials and Methods
Marcos Tobias-Machado, Cristiano Linck Pazeto, Oseas Castro Neves-Neto, Igor Nunes-Silva, Hamilton de Campos Zampolli   +4 more
doaj   +1 more source

Modified Tripier flap in reconstruction of the lower eyelid [PDF]

Anais Brasileiros de Dermatologia, 2015
We describe the use of modified Tripier flap for reconstruction of a surgical defect in the lower eyelid region, after excision of nodular basal cell carcinoma.
Walter Luiz Granado Machado, Paula Cabral de Menezes Gurfinkel, Gustavo Vieira Gualberto, Felipe Maurício Soeiro Sampaio, Marília Lopes Cavalcante Melo, Curt Mafra Treu   +5 more
doaj   +1 more source

POST OPERATIVE OUTCOME BY DIFFERENT SURGICAL PROCEDURES IN FISTULA IN ANO

, 2022
Background:Fistula-in-ano is a commonly encountered clinical entity affecting the perineal region in patients which causes significant embaressment to the patient and affects their routine day to day life. This study was undertaken to study the clinical presentation, various surgical modalities of treatment and its outcome, post-operative recovery and ...
Gogoi Bijit, Tasa Anadi S., Mazumdar Bimal, Nath Hemendra Chandra, Baro Atul Chandra   +3 more
openaire   +1 more source

Crohn's disease activity index and Vienna classification - Is it worthwhile to calculate before surgery? [PDF]

, 2006
Background: Crohn's disease (CD) patients with increased disease activity may reveal an increased risk for perioperative complications. The `Crohn's disease activity index' (CDAI) and the `Vienna classification' (VC) were developed for standardized ...
A. Beham, Best WR, Best WR, Dirks E, Friedman S, Goebell H, Greenstein AJ, H.J. Schlitt, Heimann TM, K.W. Jauch, Kiran RP, Lichtenstein GR, M. Rentsch, Mekhjian HS, Michelassi F, Murch SH, Otterson MF, Post S, Post S, Post S, Raab Y, Scholmerich J, Shepherd HA, Speranza V, Veloso FT, Wettergren A, Whelan G, Yamamoto T, Yamamoto T, Yamamoto T   +29 more
core   +1 more source

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

FEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello, Marcella Maringolo Cristovão, Guilherme Henrique, Vinicius Gonçalves Rodrigues, Caroline Serrano‐Nascimento, Edna Teruko Kimura, Cesar Seigi Fuziwara   +6 more
wiley   +1 more source

Pediatric Hand Surgery Training in Nicaragua: A Sustainable Model of Surgical Education in a Resource-Poor Environment. [PDF]

, 2017
Recent reports have demonstrated that nearly two-thirds of the world's population do not have access to adequate surgical care, a burden that is borne disproportionately by residents of resource-poor countries.
James, Michelle A, Manske, Mary Claire B, Rios Roque, Jairo J, Zelaya, Gabriel Ramos   +3 more
core   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Long-term functional outcomes and surgical retreatment after thulium laser enucleation of the prostate: A 10-year follow-up study [PDF]

International Brazilian Journal of Urology
Background: To evaluate the 10-year functional outcomes (primary) and frequency and predictors of BPH surgical retreatment (secondary) after ThuLEP. Materials and Methods: A single-center retrospective analysis of consecutive patients undergoing ThuLEP ...
Celeste Manfredi, Luigi Napolitano, Francesco Ditonno, Giovanni Maria Fusco, Carmelo Quattrone, Marco De Sio, Luca Romis, Filippo Riccardo, Maria Rosaria Nugnes, Giovanni Di Lauro, Francesco Trama   +10 more
doaj   +1 more source