Results 81 to 90 of about 418,377 (292)

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

open access: yesMolecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes   +20 more
wiley   +1 more source

A safe teaching protocol of LRP (Laparoscopic Radical Prostatectomy)

open access: yesInternational Brazilian Journal of Urology
Purpose The LRP has a steep learning curve to obtain proficiency during which patient safety may be compromised. We present an adapted modular training system which purpose to optimize the learning curve and perform a safe surgery. Materials and Methods
Marcos Tobias-Machado   +4 more
doaj   +1 more source

Considerations for the Management of Medial Orbital Wall Blowout Fracture

open access: yesArchives of Plastic Surgery, 2016
Recently, diagnoses of and operations for medial orbital blowout fracture have increased because of the development of imaging technology. In this article, the authors review the literature, and overview the accumulated knowledge about the orbital ...
Yong-Ha Kim   +2 more
doaj   +1 more source

Peritoneal adhesions after laparoscopic gastrointestinal surgery [PDF]

open access: yes, 2014
Although laparoscopy has the potential to reduce peritoneal trauma and post-operative peritoneal adhesion formation, only one randomized controlled trial and a few comparative retrospective clinical studies have addressed this issue.
MAIS, VALERIO
core   +1 more source

POST OPERATIVE OUTCOME BY DIFFERENT SURGICAL PROCEDURES IN FISTULA IN ANO

open access: yes, 2022
Background:Fistula-in-ano is a commonly encountered clinical entity affecting the perineal region in patients which causes significant embaressment to the patient and affects their routine day to day life. This study was undertaken to study the clinical presentation, various surgical modalities of treatment and its outcome, post-operative recovery and ...
Gogoi Bijit, Tasa Anadi S.   +3 more
openaire   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

open access: yesMolecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti   +10 more
wiley   +1 more source

Surgical management of the cases with both biliary and duodenal obstruction

open access: yesGastrointestinal Intervention, 2018
Endoscopic management is presently the recommended first-line of treatment for biliary strictures. However, surgery still has an important role especially for biliary obstruction (BO) with duodenal obstruction.
Yoshihiro Miyasaka   +5 more
doaj   +1 more source

The Use of Audio in Minimal Access Surgery [PDF]

open access: yes, 1999
In minimal access surgery (MAS) (also known as minimally invasive surgery), operations are carried out by making small incisions in the skin and inserting special apparatus into potential body cavities through those incisions. Laparoscopic MAS procedures
Imam, Atique, Vickers, Paul
core  

Home - About - Disclaimer - Privacy