Results 71 to 80 of about 1,872,691 (256)
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Traumatic rupture of the aorta : a case report and discussion of clinical features [PDF]
, 2012 A young female patient was involved in a head-on collision and sustained a rupture of the aortic isthmus. She underwent emergency surgical repair of an aortic pseudo-aneurysm with an interposition graft.
Manche, Alexander +3 more
core
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Spontaneous aortic sealing with tranexamic acid in type a dissection: a novel life-saving finding
European Journal of Case Reports in Internal MedicineAortic dissection is a life-threatening cardiovascular emergency, particularly Stanford type A, which typically necessitates urgent surgical intervention.
Antonio Al Hazzouri +3 more
doaj +1 more source
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
FEBS Letters, EarlyView.Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
Functional results following surgical repair of post-traumatic hand tendon injuries [PDF]
, 2016 Introduction: The study aims to determine whether early physical therapy following hand tendon repair gives better results and to look at any possible limiting factors locally.
Mifsud, Max, Zammit, Jason, Bugeja, Mark
core
Journal of the Indian Academy of Echocardiography & Cardiovascular ImagingSinus of Valsalva (SOV) aneurysm is a benign congenital cardiac anomaly that can remain asymptomatic until the rupture occurs, leading to dramatic hemodynamic effects. Ruptured SOV (RSOV) can produce interventricular dissection, valvular dysfunction, and
Manjusree Guha +2 more
doaj +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Clinical Case ReportsTimely diagnosis and management of coronary artery fistulas are vital to prevent complications. Advanced imaging and multidisciplinary care aid accurate treatment. Clinicians should consider coronary artery fistula in unexplained cardiac symptoms.
Mohammad Qaiser Aziz Khan +4 more
doaj +1 more source