Results 21 to 30 of about 106,217 (219)

Lotus leaf flavonoids induce apoptosis of human lung cancer A549 cells through the ROS/p38 MAPK pathway

Biological Research, 2021
Background Leaves of the natural plant lotus are used in traditional Chinese medicine and tea production. They are rich in flavonoids. Methods In this study, lotus leaf flavonoids (LLF) were applied to human lung cancer A549 cells and human small cell ...
Xiang-Bo Jia, Quan Zhang, Lei Xu, Wen-Jian Yao, Li Wei   +4 more
doaj   +1 more source

N6-methyladenosine Regulator-Mediated Immune Genes Identify Breast Cancer Immune Subtypes and Predict Immunotherapy Efficacy

Frontiers in Genetics, 2021
Breast cancer (BRCA) is a heterogeneous malignancy closely related to the tumor microenvironment (TME) cell infiltration. N6-methyladenosine (m6A) modification of mRNA plays a crucial regulator in regulating the immune microenvironment of BRCA ...
Meng-Meng Zhang, Meng-Meng Zhang, Yi-Lin Lin, Wen-Feng Zeng, Yang Li, Yang Yang, Miao Liu, Ying-Jiang Ye, Ke-Wei Jiang, Shu Wang, Shu Wang, Shan Wang   +11 more
doaj   +1 more source

High prevalence of false positive SARS-CoV2 serology in a cohort of patients with liver autoimmune diseases

Exploration of Medicine, 2021
Aim: Monitoring the prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) immunization in patients with autoimmune diseases is of particular concern to understand their response to the infection and to the vaccine.
Maria Giulia Cornacchia, Moris Sangineto, Rosanna Villani, Francesco Cavallone, Giuseppe Di Gioia, Paola Cicciomessere, Gaetano Serviddio   +6 more
doaj   +1 more source

Liver Ultrasound Elastography in Non-Alcoholic Fatty Liver Disease: A State-of-the-Art Summary

Diagnostics, 2023
Non-alcoholic fatty liver disease (NAFLD) is a chronic disease which is currently the most common hepatic disorder affecting up to 38% of the general population with differences according to age, country, ethnicity and sex. Both genetic and acquired risk
Rosanna Villani, Pierluigi Lupo, Moris Sangineto, Antonino Davide Romano, Gaetano Serviddio   +4 more
doaj   +1 more source

Surgical treatment of insulinoma

Journal of British Surgery, 1994
Abstract The role of preoperative and intraoperative procedures for the localization of insulinoma has been extensively debated. Transhepatic portal vein sampling before surgery has been recommended when other tests fail to localize the tumour.
PEDRAZZOLI, SERGIO, PASQUALI, CLAUDIO, ALFANO D'ANDREA A.   +2 more
openaire   +3 more sources

Surgical Treatment of Epilepsy [PDF]

Continuum, 2013
This article outlines indications for neurosurgical treatment of epilepsy, describes the presurgical workup, summarizes surgical approaches, and details expected risks and benefits.There is class I evidence for the efficacy of temporal lobectomy in treating intractable seizures, and accumulating documentation that successful surgical treatment reverses
John W, Miller, Shahin, Hakimian
openaire   +2 more sources

tRFTars: predicting the targets of tRNA-derived fragments

Journal of Translational Medicine, 2021
Background tRNA-derived fragments (tRFs) are 14–40-nucleotide-long, small non-coding RNAs derived from specific tRNA cleavage events with key regulatory functions in many biological processes.
Qiong Xiao, Peng Gao, Xuanzhang Huang, Xiaowan Chen, Quan Chen, Xinger Lv, Yu Fu, Yongxi Song, Zhenning Wang   +8 more
doaj   +1 more source

Circ_0089823 reinforces malignant behaviors of non-small cell lung cancer by acting as a sponge for microRNAs targeting SOX4,

Neoplasia: An International Journal for Oncology Research, 2021
In recent years, increasing evidence indicates the significant roles of circRNAs in carcinogenesis. However, their roles in lung cancer remain largely unclear.
Jiwei Li, Zibo Zhu, Saisai Li, Zhijun Han, Fannuo Meng, Li Wei   +5 more
doaj   +1 more source

Survival landscape of different tumor regression grades and pathologic complete response in rectal cancer after neoadjuvant therapy based on reconstructed individual patient data

BMC Cancer, 2021
Background Neoadjuvant therapy can lead to different tumor regression grades (TRG) in rectal cancer after neoadjuvant therapy. The purposes of this study are to investigate the relationships among TRG, pathologic complete response (pCR) and long-term ...
Jia-yi Li, Xuan-zhang Huang, Peng Gao, Yong-xi Song, Xiao-wan Chen, Xing-er Lv, Yv Fu, Qiong Xiao, Shi-yv Ye, Zhen-ning Wang   +9 more
doaj   +1 more source

Acute effects of insulin and insulin‐induced hypoglycaemia on carotid body chemoreceptor activity and cardiorespiratory responses in dogs

Experimental Physiology, 2023
The carotid body chemoreceptors (CBC) play an important role in the adaptive counter‐regulatory response to hypoglycaemia by evoking the CBC‐mediated sympathetic neuronal system to restore normoglycaemia.
Santhosh M. Baby, Faisal Zaidi, Gerald E. Hunsberger, David Sokal, Isha Gupta, Silvia V. Conde, Daniel Chew, Kristen Rall, Robert W. Coatney   +8 more
doaj   +1 more source