Results 81 to 90 of about 15,686,169 (410)

Advanced Breast Cancer: Case Reports and Statistical Analysis

Acta Medica Bulgarica
Breast cancer is a pathology associated with high morbidity and mortality among women of all nations worldwide. The low efficiency or total absence of national screening programs, the presence of comorbid mental illnesses or dementia, general lack of ...
Sopotenski S., Aleksandrova E., Petrov S., Lytvynenko I.   +3 more
doaj   +1 more source

Surgical versus non-surgical treatment for lumbar spinal stenosis.

Cochrane Database of Systematic Reviews, 2016
BACKGROUND Lumbar spinal stenosis (LSS) is a debilitating condition associated with degeneration of the spine with aging. OBJECTIVES To evaluate the effectiveness of different types of surgery compared with different types of non-surgical interventions
F. Zaina, C. Tomkins-Lane, E. Carragee, S. Negrini   +3 more
semanticscholar   +1 more source

Surgical treatment of a rare case of bilateral ptosis due to localized ocular amyloidosis [PDF]

, 2016
We describe a rare case of a 31-year old woman with bilateral ptosis due to localized amyloidosis. She referred a nine-year history of ptosis and surgical treatment with frontalis suspension three years previously.
ABDOLRAHIMZADEH, SOLMAZ, MAZZOCCHI, Marco, RECUPERO, Santi Maria, SCUDERI, GIANLUCA, TROCCOLA, Antonietta   +4 more
core   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

FEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan, Lu Qi, Pierre Zalloua   +2 more
wiley   +1 more source

Surgical treatment of obesity [PDF]

F1000Research, 2018
Obesity prevalence continues to increase worldwide, as do the numerous chronic diseases associated with obesity, including diabetes, non-alcoholic fatty liver disease, dyslipidemia, and hypertension. The prevalence of bariatric surgery also continues to increase and remains the most effective and sustainable treatment for obesity. Over the last several
Vance L. Albaugh, Naji N. Abumrad
openaire   +3 more sources

Single-center experience in the treatment of visceral artery aneurysms [PDF]

, 2019
Background: Visceral artery aneurysms (VAAs), although rare, represent a life-threatening disease with high mortality rates. With the more frequent use of diagnostic tests, there has been an incidental detection of these lesions which are mostly ...
Di Girolamo, A., Gattuso, R., Giglio, A., Gossetti, B., Irace, L., Martinelli, O.   +5 more
core   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Molecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane, Jérôme Ambroise, Cédric van Marcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux   +16 more
wiley   +1 more source

A signature of 24 aging‑related gene pairs predict overall survival in gastric cancer

BioMedical Engineering OnLine, 2021
Background Aging is the major risk factor for most human cancers. We aim to develop and validate a reliable aging-related gene pair signature (ARGPs) to predict the prognosis of gastric cancer (GC) patients.
Yankai Zhang, Yichao Yan, Ning Ning, Zhanlong Shen, Yingjiang Ye   +4 more
doaj   +1 more source

Circ_0049447 acts as a tumor suppressor in gastric cancer through reducing proliferation, migration, invasion, and epithelial-mesenchymal transition

Chinese Medical Journal, 2021
. Background:. Although increasing abnormal expression of circular RNAs (circRNAs) has been revealed in various cancers, there were a small number of studies about circRNAs in gastric cancer (GC).
Kai-Wen Tang, Zhe-Xu Guo, Zhong-Hua Wu, Cen Zhou, Jie Sun, Xin Wang, Yong-Xi Song, Zhen-Ning Wang, Li-Shao Guo   +8 more
doaj   +1 more source

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi, Eric Feng, Nicholas R. Rydzewski, Amy K. Taylor, Jamie M. Sperger, Yue Shi, Kyle T. Helzer, Matthew L. Bootsma, Viridiana Carreno, Alex H. Chang, Luke A. Nunamaker, Grace C. Blitzer, Tianfu Andy Shang, Aishwarya Subramanian, Anders Bjartell, Andreas Josefsson, Pernilla Wikström, Emily Feng, Manish Kohli, Rendong Yang, Scott M. Dehm, Eric J. Small, Rahul Aggarwal, David A. Quigley, Joshua M. Lang, Shuang G. Zhao, Martin Sjöström   +26 more
wiley   +1 more source