Results 61 to 70 of about 108,248 (272)

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Clinical guidelines as plans: An ontological theory [PDF]

, 2006
Clinical guidelines are special types of plans realized by collective agents. We provide an ontological theory of such plans that is designed to support the construction of a framework in which guideline-based information systems can be employed in the ...
Gangemi, Aldo, Kumar, Anand, Pisanelli, Domenica, Smith, Barry, Stefanelli, Mario   +4 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Augmented reality in computer-assisted interventions based on patient-specific 3D printed reference

Healthcare Technology Letters, 2018
Augmented reality (AR) can be an interesting technology for clinical scenarios as an alternative to conventional surgical navigation. However, the registration between augmented data and real-world spaces is a limiting factor.
Rafael Moreta-Martinez, David García-Mato, Mónica García-Sevilla, Rubén Pérez-Mañanes, José Calvo-Haro, Javier Pascau   +5 more
doaj   +1 more source

Surgical Phase Recognition of Short Video Shots Based on Temporal Modeling of Deep Features

, 2018
Recognizing the phases of a laparoscopic surgery (LS) operation form its video constitutes a fundamental step for efficient content representation, indexing and retrieval in surgical video databases.
Loukas, Constantinos
core   +1 more source

Rapid detection of copy number variations and point mutations in BRCA1/2 genes using a single workflow by ion semiconductor sequencing pipeline [PDF]

, 2018
Molecular analysis of BRCA1 (MIM# 604370) and BRCA2 (MIM #600185) genes is essential for familial breast and ovarian cancer prevention and treatment.
Amanti, C, De Marchis, L, Germani, A, Libi, F, Lombardi, A, Maggi, S, Mattei, M, Pellegrini, P, Piane, M, Pizzuti, A, Stanzani., G, Torrisi, Mr   +11 more
core   +1 more source

Workflow disruptions and surgical performance: past, present and future [PDF]

BMJ Quality & Safety, 2019
The earliest contributions of human factors engineering to surgery probably occurred just over a century ago. Already well-known for their pioneering scientific approaches to management, Frank and Lillian Gilbreth turned their expertise in time and motion studies and the psychology of management to optimising the operating room environment (and various
Douglas A, Wiegmann, Thoralf M, Sundt
openaire   +2 more sources

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Enhancing Surgical Workflows through DICOM

Current Directions in Biomedical Engineering
The Digital Imaging and Communications in Medicine (DICOM) standard has evolved from a radiological data exchange protocol into a foundational element for surgical informatics.
Härtl Isabel, Junger Denise, Beyersdorffer Patrick, Burgert Oliver, Kücherer Christian   +4 more
doaj   +1 more source

Towards Graph Representation Learning Based Surgical Workflow Anticipation

2022 IEEE-EMBS International Conference on Biomedical and Health Informatics (BHI), 2022
Surgical workflow anticipation can give predictions on what steps to conduct or what instruments to use next, which is an essential part of the computer-assisted intervention system for surgery, e.g. workflow reasoning in robotic surgery. However, current approaches are limited to their insufficient expressive power for relationships between ...
Francis Xiatian Zhang, Noura Al Moubayed, Hubert P. H. Shum   +2 more
openaire   +3 more sources