Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Creating and validating a patient-reported outcome instrument for women with vulvar neoplasia after surgical treatment : a mixed-methods project [PDF]
In vulvar neoplasia, substantial improvements in therapy and care have been attained during the last decades.1 Nevertheless even minor surgical interventions cause multiple symptoms and side effects that impact women’s quality of life.2 The term ...
Senn, Beate
core +1 more source
NEGATIVE-PRESSURE WOUND THERAPY IN THE TREATMENT OF COMPLEX INJURIES AFTER TOTAL KNEE ARTHROPLASTY [PDF]
Objective: To present an experience with negative-pressure wound therapy (NPWT) in the treatment of surgical wounds in patients treated for infections after total knee arthroplasty (TKA) with or without dehiscence and prophylaxis in wounds considered at
Camilo Partezani Helito +5 more
doaj +1 more source
Nonpharmacological Prevention of Surgical Wound Infections [PDF]
Postoperative wound infection is a common and serious complication of surgery. This review will focus on 2 factors known to modulate perioperative immunity: maintenance of perioperative normothermia and provision of supplemental perioperative oxygen. Hypothermia causes numerous adverse outcomes, including morbid myocardial events, increased blood loss ...
Daniel I, Sessler, Ozan, Akça
openaire +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Impact of changing the surgical team for wound closure on surgical site infection: A matched case-control study. [PDF]
BACKGROUND Wound closure is performed at the end of the procedure, when the attention of the surgical team may decrease due to tiredness. The aim of this study was to assess the influence of changing the surgical team for wound closure on the rate of ...
Chapalley, Dimitri +11 more
core +1 more source
Risk factors incidence of surgical wound infection following abdominal hysterectomy
Background and Objective: Surgical wound infection is the most common complication following surgery. This study was done to determine the incidence risk factors of surgical wound infection following abdominal hysterectomy.
Yazdani Sh +4 more
doaj
published_or_final_version
Soundara Rajan, S +4 more
openaire +2 more sources
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Bacteriological Spectrum of Post Operative Wound Infections and their Antibiogram in a Tertiary Hospital, Dar es salaam, Tanzania [PDF]
Surgical site infection (SSI) is among the most common problem for patients who undergo operative procedures. It remains a common and widespread problem contributing to morbidity and mortality; partly attributed to increase in infections due to ...
Manyahi, Joel, Manyahi, J.
core

