Results 51 to 60 of about 200,358 (263)

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Outcomes of vascular surgeon-performed rectus femoris flaps for complex postoperative wound infection

Journal of Vascular Surgery Cases and Innovative Techniques
Objective: Rectus femoris flaps (RFFs) provide tissue coverage in infected fields and historically have been performed by plastic surgeons. Methods: We report the technique and outcomes following vascular surgeon-performed RFFs for postoperative groin ...
Shiza Bari, BS, Kristy Wrana, RN, Ya-Huei Li, PhD, Zachary Chadnick, MD, Parth Shah, MD, Thomas Divinagracia, MD, Mary Windels, MD, James Gallagher, III, MD, Elizabeth Aitcheson, MD, Akhilesh Jain, MD, Owen Glotzer, MD, Mouhanad Ayach, MD, Edward Gifford, MD   +12 more
doaj   +1 more source

Risk factors for postoperative infection of odontogenic cysts associated with mandibular third molar

Maxillofacial Plastic and Reconstructive Surgery, 2020
Background Odontogenic cysts associated with lower third molar are common. The prognosis for surgical treatment is relatively good. However, postoperative infection discourages the clinicians.
Jin-woo Kim, Do-hyun On, Jin-yong Cho, Jaeyoung Ryu   +3 more
doaj   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

Surgical Site Infection After Breast Surgery—A Bicentric Retrospective Case–Control Study in Saudi Arabia

Clinics and Practice
Background: Surgical site infections (SSIs) are common postoperative complications. Data on SSIs following breast surgery in Saudi Arabia are limited because these procedures are not included in the national SSI surveillance system. This study determined
Moteb AlSaadi, Salem Alghamdi, Fayyaz Mazari, Sabah Alshuhri, Rustom Bashtawi, Raghad Aljehani, Basmah Alwuqaisi, Rawan Almohammadi, Mahmoud Alfirikh, Sameer Desai, Ebrahim Mahmoud   +10 more
doaj   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

FROM WHATSAPP TO PREDICTION: HOW AUTOMATION TRANSFORMED POST-DISCHARGE SURVEILLANCE OF SURGICAL INFECTIONS

Brazilian Journal of Infectious Diseases
Introduction: Brazilian legislation requires post-discharge surveillance of surgical patients to control Surgical Site Infections (SSI), but the process faces challenges such as difficulty in follow-up, communication failures, and high costs of ...
Bráulio Roberto Gonçalves Marinho Couto, Hoberdan Oliveira Pereira, Ana Paula Ladeira, Rossana Souza, Felipe Campolina Soares de Paula, Marcelo Reis Esteves, Débora Figueiredo Souza, Henrique de Almeida Diniz, Bernardo Lara Afonso   +8 more
doaj   +1 more source

Clinical Outcomes of SEEG‐Guided Radiofrequency Thermocoagulation in Children With Focal Drug‐Resistant Epilepsy: A Multicenter Real‐World Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stereoelectroencephalography‐guided radiofrequency thermocoagulation (SEEG‐RFTC) has emerged as a safe and effective minimally invasive treatment for children with drug‐resistant focal epilepsy. Although evidence from real‐world studies remains limited, numerous pediatric cases have demonstrated promising outcomes. This retrospective
Weitao Chen, Stéphane Jean, Weihong Liu, Yihai Dai, Xinrong Fang, Xiaoqiang Wei, Shan Chen, Shiwei Song   +7 more
wiley   +1 more source

Infecção latente de sítio cirúrgico: hipótese ou realidade?

Revista do Colégio Brasileiro de Cirurgiões
OBJETIVO: A infecção prévia do sítio cirúrgico é um forte determinante para o desenvolvimento de uma nova infecção do sítio cirúrgico. É a chamada infecção latente do sítio cirúrgico.
Álvaro Antônio Bandeira Ferraz, Edmundo Machado Ferraz   +1 more
doaj   +1 more source