Results 221 to 230 of about 1,277,935 (286)

A Self‐Organized Liquid Reaction Container for Cellular Memory

Advanced Science, EarlyView.
How cells restore epigenetic information lost during replication is not known. This work proposes a mechanism based on the formation of biomolecular condensates. These condensates are induced by the chromosome itself and serve as reaction vessels for reconstructing missing epigenetic markers.
Sukanta Mukherjee, Enrico Skoruppa, Holger Merlitz, Jens‐Uwe Sommer, Helmut Schiessel   +4 more
wiley   +1 more source

The Somatosensory Mismatch Negativity. [PDF]

Eur J Neurosci
Grundei M, von der Behrens W, Astikainen P, Wetzel N, Blankenburg F.   +4 more
europepmc   +1 more source

Astrocytic PCBP1 Suppresses Ferroptosis to Restore Glutamatergic Homeostasis and Mitigate Stress‐Induced Depression in Male Mice

Advanced Science, EarlyView.
This study demonstrates that polyC‐RNA‐binding protein 1 (PCBP1) in ventral hippocampal astrocytes modulates depressive‐like behaviors by regulating glutathione peroxidase 4‐mediated ferroptosis and synaptic glutamatergic transmission. PCBP1 overexpression intervention in the chronic unpredictable mild stress model rescues behavioral deficits ...
Jinyu Zhang, Binbin Zhao, Min Jia, Yan Zhao, Ye Lu, Wenyu Xi, Ziyu Zhu, Xiaojuan Gong, Qingyan Ma, Yuan Gao, Yijie Guo, Pan Li, Feng Zhu, Shuguang Wei, Xiancang Ma, Yunpeng Wang   +15 more
wiley   +1 more source

Editorial: Ecosystem and planetary health and emerging/re-emerging zoonoses

Frontiers in Veterinary Science
Demelash Areda, Bedaso Edao
doaj   +1 more source

Inflamed Amyand's Hernia in an Elderly Male: A Rare Surgical Surprise. [PDF]

Cureus
Khan G, Niaz A, Adan M, Suleman F, Khan I, Misra AK.   +5 more
europepmc   +1 more source

Effectiveness of Multivitamins vs Folic Acid on Prevention of Neural Tube Defects in Mouse Genetic Models and Human Organoids

Advanced Science, EarlyView.
Folic acid (FA) and multivitamins/minerals (MVM) are recommended for the prevention of neural tube defects (NTDs). Using a novel human neural tube‐like organoid system and mouse models, the study compares the effectiveness of two supplements on NTDs and cellular behaviors.
Huili Li, Jing Zhang, Lori Bulwith, Lee Niswander   +3 more
wiley   +1 more source

From Social to Symbolic: Investigating the Neural Networks Involved in Emoji and Facial Expression Recognition. [PDF]

Brain Topogr
Proverbio AM, Bacciocchi L, Pavoni A.
europepmc   +1 more source

HSP70 Interactome‐Mediated Proteolysis Targeting Chimera (HSP70‐PROTAC) for Ferroptosis‐Driven Cancer Treatment

Advanced Science, EarlyView.
This study reports a novel targeted protein degradation strategy termed “HSP70‐PROTAC” that recruits Hsc70 complex to a target protein for inducing degradation. Among them, GDAz‐3 exhibits effective GPX4 degradation activity via UPS/CMA processes, triggering ferroptosis‐driven anticancer activity in vitro and in vivo.
Jinyun Dong, Yulong Li, Hui Liang, Zumei Wu, Shiqun Wang, Yichao Wang, Jieyu Xu, Yanning Lan, Maohua Cai, Guangzhao Pan, Haiyan Yang, Kai Miao, Zhe‐Sheng Chen, Fangfang Tao, Xuelei Ma, Jiang‐Jiang Qin   +15 more
wiley   +1 more source

Shared breath of joy enhances empathy through breathing synchronization. [PDF]

Sci Rep
Masaoka Y, Honma M, Nakayama M, Matsui M, Yoshikawa A, Kosuge S, Kosuge M, Shoji D, Sakakura S, Izumizaki M.   +9 more
europepmc   +1 more source

Unleashing the Potential of Raman Spectroscopy to Estimate PEDOT:PSS Doping Level and Crystalline Morphology

Advanced Science, EarlyView.
Herein, the correlational changes of each PEDOT Raman peak to morphology and doping level are identified. Two equations are derived to estimate PEDOT π–π spacing and doping level from Raman spectra (from which mobility is also extracted). GIWAXS and XPS results validate the estimation equations.
Tzu‐Yi Thomas Yu, Tsu‐Yu Chou, Viktor Naenen, Bokai Zhang, Hasan Emre Baysal, Bora Bulut, Martin Rosenthal, Francisco Molina‐Lopez   +7 more
wiley   +1 more source