Results 51 to 60 of about 1,277,935 (286)

Electrophysiological indicators of surprise and entropy in dynamic task-switching environments

open access: yesFrontiers in Human Neuroscience, 2013
This event-related brain potential (ERP) study aimed at bridging two hitherto widely separated domains of cognitive neuroscience. Specifically, we combined the analysis of cognitive control in a cued task-switching paradigm with the fundamental question ...
Bruno eKopp, Florian eLange
doaj   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

Multiscale Free Energy Analysis of Human Ecosystem Engineering

open access: yesEntropy, 2021
Unlike ecosystem engineering by other living things, which brings a relatively limited range of sensations that are connected to a few enduring survival preferences, human ecosystem engineering brings an increasing variety and frequency of novel ...
Stephen Fox
doaj   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Pupil dilation signals uncertainty and surprise in a learning gambling task

open access: yesFrontiers in Behavioral Neuroscience, 2014
Pupil dilation under constant illumination is a physiological marker which modulation is related to several cognitive functions involved in daily decision making.
Claudio eLavin   +6 more
doaj   +1 more source

An E7 Surprise

open access: yes, 2012
We explore some curious implications of Seiberg duality for an SU(2) four-dimensional gauge theory with eight chiral doublets. We argue that two copies of the theory can be deformed by an exactly marginal quartic superpotential so that they acquire an ...
A Gadde   +29 more
core   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

open access: yesFEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart   +4 more
wiley   +1 more source

Task-irrelevant expectation violations in sequential manual actions: Evidence for a “check-after-surprise” mode of visual attention and eye-hand decoupling

open access: yesFrontiers in Psychology, 2016
When performing sequential manual actions (e.g., cooking), visual information is prioritized according to the task determining where and when to attend, look, and act.
Rebecca Martina Foerster
doaj   +1 more source

Detection in the presence of surprise or undernulled interference [PDF]

open access: yes, 2007
We consider the problem of detecting a signal of interest in the presence of colored noise, in the case of a covariance mismatch between the test cell and the training samples. More precisely, we consider a situation where an interfering signal (e.g., a
Besson, Olivier
core   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

open access: yesFEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

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