Results 41 to 50 of about 364,351 (266)

Surrogate dual problems and surrogate lagrangians

open access: yesJournal of Mathematical Analysis and Applications, 1984
The author continues his study of perturbed quasiconvex duality. Various new results on surrogate Lagrangians are given and specializations are considered.
openaire   +2 more sources

On Machine-Learning-Driven Surrogates for Sound Transmission Loss Simulations

open access: yesApplied Sciences, 2022
Surrogate models are data-based approximations of computationally expensive simulations that enable efficient exploration of the model’s design space and informed decision making in many physical domains.
Barbara Zaparoli Cunha   +4 more
doaj   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta   +6 more
wiley   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli   +3 more
wiley   +1 more source

Sensitivity Analysis of C. auris, S. cerevisiae, and C. cladosporioides by Irradiation with Far-UVC, UVC, and UVB

open access: yesPathogens and Immunity
Background: The World Health Organization has published a list of pathogenic fungi with prioritizing groups and calls for research and development of antifungal measures, with Candida auris belonging to the group with high priority.
Anna-Maria Gierke, Martin Hessling
doaj   +1 more source

A Successful Induction of Lactation in Surrogate Pregnancy with Metoclopramide and Review of Lactation Induction [PDF]

open access: yesInternational Journal of Fertility and Sterility, 2010
In surrogate pregnancies genetic parents have little opportunity for early bonding with their infants either prenatally (in utero) or during the immediate postnatal period.
Marzieh Shiva   +3 more
doaj   +1 more source

Medicine and the Law

open access: yesSouth African Medical Journal, 2023
Problems arise when a lawfully appointed surrogate decision-maker wishes to decide on a course of action on behalf of a mentally incompetent patient that is against the patient’s best interests.
D J McQuoid-Mason
doaj   +1 more source

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi   +5 more
wiley   +1 more source

Effects of the Fluid Replacement Method During Online Hemodiafiltration on the Solute Removal Performance and Biocompatibility Using the Asymmetric Cellulose Triacetate Membrane

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Pre‐dilution online hemodiafiltration (Pre‐HDF) is predominantly used in Japan, whereas post‐dilution online HDF (Post‐HDF) is more common in Europe. An asymmetric cellulose triacetate (ATA) membrane may improve biocompatibility.
Kenji Sakurai   +4 more
wiley   +1 more source

Biomarkers, Putative Surrogates, Surrogates, and Decision Making [PDF]

open access: yesCirculation: Cardiovascular Imaging, 2013
The development of new therapies is slow, expensive, and frustrating. The failure rate for new molecular entities exceeds 90%, and total research and development costs per successful new molecular entity are currently estimated to be nearly $2 billion.1 Consternation about the complexity of therapeutic development recently prompted a major report by ...
openaire   +2 more sources

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